Vortex-assisted supramolecular solvent dispersive liquid–liquid microextraction of ketoprofen and naproxen from environmental water before chromatographic analysis: response surface methodology optimisation

Akawa Mpingana Ndilimeke, K. Mogolodi Dimpe, Philiswa Nosizo Nomngongo

Research output: Contribution to journalArticlepeer-review

Abstract

A microextraction procedure that is rapid and simple to extract and preconcentrate ketoprofen and naproxen is proposed. An environmentally friendly supramolecular solvent was applied as an extraction solvent and proved to be efficient in the extraction of ketoprofen and naproxen from environmental water. The design of experiment approach was used to screen, optimize significant parameters, and determine optimum experimental conditions. Under optimized experimental conditions, the vortex-assisted supramolecular solvent dispersive liquid–liquid microextraction provided a good linearity (0.57–700 µg L−1), low limits of detection (0.17–0.24 µg L−1) and extraction reproducibility below 9%. The high percentage relative recoveries (93.6–101.4%) indicated that the method is not affected by matrix. The practical applicability of the method was assessed by analysing ketoprofen and naproxen in river water and effluent wastewater samples. Both analytes were found in effluent wastewater.

Original languageEnglish
Article number47
JournalJournal of Analytical Science and Technology
Volume13
Issue number1
DOIs
Publication statusPublished - Dec 2022

Keywords

  • Central composite design
  • Dispersive liquid–liquid microextraction
  • Environmental water
  • Ketoprofen
  • Naproxen
  • Supramolecular solvent

ASJC Scopus subject areas

  • General Chemistry
  • General Materials Science
  • General Biochemistry,Genetics and Molecular Biology
  • General Environmental Science
  • General Physics and Astronomy

Fingerprint

Dive into the research topics of 'Vortex-assisted supramolecular solvent dispersive liquid–liquid microextraction of ketoprofen and naproxen from environmental water before chromatographic analysis: response surface methodology optimisation'. Together they form a unique fingerprint.

Cite this