Voltammetric detection of sulfonamides at a poly(3-methylthiophene) electrode

Titus A.M. Msagati; J. Catherine Ngila

doi:10.1016/S0039-9140(02)00327-2

Voltammetric detection of sulfonamides at a poly(3-methylthiophene) electrode

Titus A.M. Msagati, J. Catherine Ngila

University of Botswana

Research output: Contribution to journal › Article › peer-review

105 Citations (Scopus)

Abstract

Detection of sulfonamide compounds in a mixture of standards at a poly (3-methylthiophene) coated on glassy carbon (GC) electrode is reported. The polymer, poly(3-methylthiophene), was electrochemically synthesized at a GC rotating disk-working electrode versus Ag/AgCl using cyclic voltammetry (+0.5 to +2.0 V). Square wave voltammetry (SQWV) with cathodic reduction (0 to -4.0 V) was used for the detection of seven sulfonamide compounds in a mixture. The working concentration ranges (curvilinear) established for different compounds in Britton-Robinson (BR) buffer (pH 6.26), were: 5.0 x 10^-6-3.2 x 10^-3 M sulfamerazine, 5.0 x 10^-6-3.2 x 10^-3 M sulfadiazine, 7.5 x 10^-7-3.2 x 10^-4 M sulfasalazine, 9.0 x 10^-7-5.0 x 10^-4 M sulfamethazine, 6.5 x 10^-8-3.5.0 x 10^-5 M sulfamethoxazole, 9.7 x 10^-8-5.0 x 10^-5 M sulfathiazole, and 9.0 x 10^-8-3.2 x 10^-5 M 5-sulfaminouracil. Detection limits were calculated as: 3.9 x 10^-6 M for sulfamerazine; 4.0 x 10^-6 M sulfadiazine; 2.5 x 10^-7 M sulfasalazine; 3.7 x 10^-7 M sulfamethazine; 4.0 x 10^-8 M sulfamethoxazole; 6.4 x 10^-8 M sulfathiazole and 6.0 x 10^-9 M 5-sulfaminouracil. The data suggests a potential application of the poly(3-methylthiophene) (P3MT) electrode for determination of sulfonamides in veterinary and other applications.

Original language	English
Pages (from-to)	605-610
Number of pages	6
Journal	Talanta
Volume	58
Issue number	3
DOIs	https://doi.org/10.1016/S0039-9140(02)00327-2
Publication status	Published - 12 Sept 2002
Externally published	Yes

Keywords

Conducting polymers
Poly(3-methylthiophene)
Square wave voltammetry
Sulfonamides

ASJC Scopus subject areas

Analytical Chemistry

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10.1016/S0039-9140(02)00327-2

Cite this

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title = "Voltammetric detection of sulfonamides at a poly(3-methylthiophene) electrode",

abstract = "Detection of sulfonamide compounds in a mixture of standards at a poly (3-methylthiophene) coated on glassy carbon (GC) electrode is reported. The polymer, poly(3-methylthiophene), was electrochemically synthesized at a GC rotating disk-working electrode versus Ag/AgCl using cyclic voltammetry (+0.5 to +2.0 V). Square wave voltammetry (SQWV) with cathodic reduction (0 to -4.0 V) was used for the detection of seven sulfonamide compounds in a mixture. The working concentration ranges (curvilinear) established for different compounds in Britton-Robinson (BR) buffer (pH 6.26), were: 5.0 x 10-6-3.2 x 10-3 M sulfamerazine, 5.0 x 10-6-3.2 x 10-3 M sulfadiazine, 7.5 x 10-7-3.2 x 10-4 M sulfasalazine, 9.0 x 10-7-5.0 x 10-4 M sulfamethazine, 6.5 x 10-8-3.5.0 x 10-5 M sulfamethoxazole, 9.7 x 10-8-5.0 x 10-5 M sulfathiazole, and 9.0 x 10-8-3.2 x 10-5 M 5-sulfaminouracil. Detection limits were calculated as: 3.9 x 10-6 M for sulfamerazine; 4.0 x 10-6 M sulfadiazine; 2.5 x 10-7 M sulfasalazine; 3.7 x 10-7 M sulfamethazine; 4.0 x 10-8 M sulfamethoxazole; 6.4 x 10-8 M sulfathiazole and 6.0 x 10-9 M 5-sulfaminouracil. The data suggests a potential application of the poly(3-methylthiophene) (P3MT) electrode for determination of sulfonamides in veterinary and other applications.",

keywords = "Conducting polymers, Poly(3-methylthiophene), Square wave voltammetry, Sulfonamides",

author = "Msagati, {Titus A.M.} and Ngila, {J. Catherine}",

year = "2002",

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doi = "10.1016/S0039-9140(02)00327-2",

language = "English",

volume = "58",

pages = "605--610",

journal = "Talanta",

issn = "0039-9140",

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TY - JOUR

T1 - Voltammetric detection of sulfonamides at a poly(3-methylthiophene) electrode

AU - Msagati, Titus A.M.

AU - Ngila, J. Catherine

PY - 2002/9/12

Y1 - 2002/9/12

N2 - Detection of sulfonamide compounds in a mixture of standards at a poly (3-methylthiophene) coated on glassy carbon (GC) electrode is reported. The polymer, poly(3-methylthiophene), was electrochemically synthesized at a GC rotating disk-working electrode versus Ag/AgCl using cyclic voltammetry (+0.5 to +2.0 V). Square wave voltammetry (SQWV) with cathodic reduction (0 to -4.0 V) was used for the detection of seven sulfonamide compounds in a mixture. The working concentration ranges (curvilinear) established for different compounds in Britton-Robinson (BR) buffer (pH 6.26), were: 5.0 x 10-6-3.2 x 10-3 M sulfamerazine, 5.0 x 10-6-3.2 x 10-3 M sulfadiazine, 7.5 x 10-7-3.2 x 10-4 M sulfasalazine, 9.0 x 10-7-5.0 x 10-4 M sulfamethazine, 6.5 x 10-8-3.5.0 x 10-5 M sulfamethoxazole, 9.7 x 10-8-5.0 x 10-5 M sulfathiazole, and 9.0 x 10-8-3.2 x 10-5 M 5-sulfaminouracil. Detection limits were calculated as: 3.9 x 10-6 M for sulfamerazine; 4.0 x 10-6 M sulfadiazine; 2.5 x 10-7 M sulfasalazine; 3.7 x 10-7 M sulfamethazine; 4.0 x 10-8 M sulfamethoxazole; 6.4 x 10-8 M sulfathiazole and 6.0 x 10-9 M 5-sulfaminouracil. The data suggests a potential application of the poly(3-methylthiophene) (P3MT) electrode for determination of sulfonamides in veterinary and other applications.

AB - Detection of sulfonamide compounds in a mixture of standards at a poly (3-methylthiophene) coated on glassy carbon (GC) electrode is reported. The polymer, poly(3-methylthiophene), was electrochemically synthesized at a GC rotating disk-working electrode versus Ag/AgCl using cyclic voltammetry (+0.5 to +2.0 V). Square wave voltammetry (SQWV) with cathodic reduction (0 to -4.0 V) was used for the detection of seven sulfonamide compounds in a mixture. The working concentration ranges (curvilinear) established for different compounds in Britton-Robinson (BR) buffer (pH 6.26), were: 5.0 x 10-6-3.2 x 10-3 M sulfamerazine, 5.0 x 10-6-3.2 x 10-3 M sulfadiazine, 7.5 x 10-7-3.2 x 10-4 M sulfasalazine, 9.0 x 10-7-5.0 x 10-4 M sulfamethazine, 6.5 x 10-8-3.5.0 x 10-5 M sulfamethoxazole, 9.7 x 10-8-5.0 x 10-5 M sulfathiazole, and 9.0 x 10-8-3.2 x 10-5 M 5-sulfaminouracil. Detection limits were calculated as: 3.9 x 10-6 M for sulfamerazine; 4.0 x 10-6 M sulfadiazine; 2.5 x 10-7 M sulfasalazine; 3.7 x 10-7 M sulfamethazine; 4.0 x 10-8 M sulfamethoxazole; 6.4 x 10-8 M sulfathiazole and 6.0 x 10-9 M 5-sulfaminouracil. The data suggests a potential application of the poly(3-methylthiophene) (P3MT) electrode for determination of sulfonamides in veterinary and other applications.

KW - Conducting polymers

KW - Poly(3-methylthiophene)

KW - Square wave voltammetry

KW - Sulfonamides

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U2 - 10.1016/S0039-9140(02)00327-2

DO - 10.1016/S0039-9140(02)00327-2

M3 - Article

AN - SCOPUS:0037068517

SN - 0039-9140

VL - 58

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EP - 610

JO - Talanta

JF - Talanta

IS - 3

ER -

Voltammetric detection of sulfonamides at a poly(3-methylthiophene) electrode

Abstract

Keywords

ASJC Scopus subject areas

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