Tumor cryotherapy using Ice-producing bacteria

Mohammad Reza Atashzar, Michael R. Hamblin, Farajolah Maleki, Ebrahim Kouhsari

Research output: Contribution to journalLetterpeer-review

1 Citation (Scopus)


One of he approaches to cancer treatment is cryotherapy. In this therapy low temperatures lead to freezing and killing the cancer cells. Low temperature has several side effects on the health of tissues. Using bacteria for treatment of cancer as a therapeutic approach is proposed. One of the bacteria is Pseudomonas syringe with ice-producing properties. In this study, we hypothesized that by insertion of INA gene of P. syringe into anaerobic bacteria can do cryotherapy at a low temperature. This hypothesis is based on the manipulated anaerobic bacteria moves to the side of the tumor from ice crystal.

Original languageEnglish
Article number110101
JournalMedical Hypotheses
Publication statusPublished - Nov 2020
Externally publishedYes


  • Anaerobic bacteria
  • Cryotherapy
  • INA gene
  • Pseudomonas syringe

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Tumor cryotherapy using Ice-producing bacteria'. Together they form a unique fingerprint.

Cite this