Traditional Uses and Bioactivities of Common Rubus Species With Reference to Cancer: A Mini-Review

Rubus, recognized as one of the largest plant genus, from the family Rosaceae, is widely distributed for their distinguished health benefits and has long been known as a source of food and medicine for native community soon after the glacial period. It is evident that berries were categorized as powerful disease fighting food that had been in use as traditional medicine for numerous ailments. Most of the berries are bright colored and has a flavorful taste such as blackberry, raspberry and strawberry, which makes up a popular fruit in human nutrition and diet. Research established the presence of bioactive phytochemicals in Rubus which is responsible for suppressing tumor cell proliferation by various inhibitory mechanisms in the cell signaling which leads to cell death. Plant extracts have antiviral, antibacterial and immunological properties and research correlates the need for the intake of fruits and vegetables rich diet to lessen the risk of global mortality rates related to cancer and cardiovascular diseases. This review focuses on various medical applications of Rubus species, its traditional uses, and the bioactive compounds responsible for the activities with special reference to cancer.