The Synthesis of Optically Pure PCyclopiazonic Acid, an Indolic Fungal Metabolite

Cedric W. Holzapfel; Friedrich W.H. Kruger

doi:10.1071/CH9920099

The Synthesis of Optically Pure PCyclopiazonic Acid, an Indolic Fungal Metabolite

Cedric W. Holzapfel
, Friedrich W.H. Kruger

Chemical Sciences

University of Johannesburg

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The chiral synthesis of the fungal metabolite fi-cyclopiazonic acid is described. The key step involves the use of the tricarbonylchromium complex of an N-protected L-tryptophan methyl ester as a substrate for the addition/oxidation method of substitution of its indole ring system.

Original language	English
Pages (from-to)	99-107
Number of pages	9
Journal	Australian Journal of Chemistry
Volume	45
Issue number	1
DOIs	https://doi.org/10.1071/CH9920099
Publication status	Published - 1992

ASJC Scopus subject areas

General Chemistry

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10.1071/CH9920099

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title = "The Synthesis of Optically Pure PCyclopiazonic Acid, an Indolic Fungal Metabolite",

abstract = "The chiral synthesis of the fungal metabolite fi-cyclopiazonic acid is described. The key step involves the use of the tricarbonylchromium complex of an N-protected L-tryptophan methyl ester as a substrate for the addition/oxidation method of substitution of its indole ring system.",

author = "Holzapfel, \{Cedric W.\} and Kruger, \{Friedrich W.H.\}",

year = "1992",

doi = "10.1071/CH9920099",

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journal = "Australian Journal of Chemistry",

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T1 - The Synthesis of Optically Pure PCyclopiazonic Acid, an Indolic Fungal Metabolite

AU - Holzapfel, Cedric W.

AU - Kruger, Friedrich W.H.

PY - 1992

Y1 - 1992

N2 - The chiral synthesis of the fungal metabolite fi-cyclopiazonic acid is described. The key step involves the use of the tricarbonylchromium complex of an N-protected L-tryptophan methyl ester as a substrate for the addition/oxidation method of substitution of its indole ring system.

AB - The chiral synthesis of the fungal metabolite fi-cyclopiazonic acid is described. The key step involves the use of the tricarbonylchromium complex of an N-protected L-tryptophan methyl ester as a substrate for the addition/oxidation method of substitution of its indole ring system.

UR - https://www.scopus.com/pages/publications/84970583501

U2 - 10.1071/CH9920099

DO - 10.1071/CH9920099

M3 - Article

AN - SCOPUS:84970583501

SN - 0004-9425

VL - 45

SP - 99

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JO - Australian Journal of Chemistry

JF - Australian Journal of Chemistry

IS - 1

ER -

The Synthesis of Optically Pure PCyclopiazonic Acid, an Indolic Fungal Metabolite

Abstract

ASJC Scopus subject areas

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