The HF/BF3-catalysed reaction of substituted benzenes with carbon monoxide

J. Alexander Willemse, Barend C.B. Bezuidenhoudt, Cedric W. Holzapfel

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


The HF/BF3-catalysed reactions of phenol and anisole as well as substituted benzenes with CO were investigated as possible routes to commercially important aldehydes. The results confirmed that HF and BF 3 are required in (at least) stoichiometric amounts for effective formylation with CO. With the aim of effecting truly catalytic reaction conditions, the formylation reactions were carried out in ionic liquids. It was shown that phenol is a good substrate for formylation in certain ionic liquids.

Original languageEnglish
Pages (from-to)2543-2550
Number of pages8
Issue number15
Publication statusPublished - 1 Aug 2006


  • Aldehydes
  • Electrophilic aromatic substitutions
  • Ionic liquids
  • Lewis acids
  • Phenols

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry


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