The conversion of sterigmatocystin into dihydroaspertoxin

R. D. Hutchison; C. W. Holzapfel

doi:10.1016/S0040-4020(01)90712-4

The conversion of sterigmatocystin into dihydroaspertoxin

R. D. Hutchison, C. W. Holzapfel

Council for Scientific and Industrial Research

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Treatment of O-methyldihydrosterigmatocystin (III) with methanolic alkali under vigorous conditions effected opening of the furan ring to give the compound Va. Reaction of the corresponding acetate with lead tetra-acetate gave dihydroaspertoxin acetate which was converted into dihydroaspertoxin (VIb) by hydrolysis with dilute alkali.

Original language	English
Pages (from-to)	425-431
Number of pages	7
Journal	Tetrahedron
Volume	27
Issue number	2
DOIs	https://doi.org/10.1016/S0040-4020(01)90712-4
Publication status	Published - 1971
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4020(01)90712-4

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title = "The conversion of sterigmatocystin into dihydroaspertoxin",

abstract = "Treatment of O-methyldihydrosterigmatocystin (III) with methanolic alkali under vigorous conditions effected opening of the furan ring to give the compound Va. Reaction of the corresponding acetate with lead tetra-acetate gave dihydroaspertoxin acetate which was converted into dihydroaspertoxin (VIb) by hydrolysis with dilute alkali.",

author = "Hutchison, {R. D.} and Holzapfel, {C. W.}",

year = "1971",

doi = "10.1016/S0040-4020(01)90712-4",

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AU - Hutchison, R. D.

AU - Holzapfel, C. W.

PY - 1971

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N2 - Treatment of O-methyldihydrosterigmatocystin (III) with methanolic alkali under vigorous conditions effected opening of the furan ring to give the compound Va. Reaction of the corresponding acetate with lead tetra-acetate gave dihydroaspertoxin acetate which was converted into dihydroaspertoxin (VIb) by hydrolysis with dilute alkali.

AB - Treatment of O-methyldihydrosterigmatocystin (III) with methanolic alkali under vigorous conditions effected opening of the furan ring to give the compound Va. Reaction of the corresponding acetate with lead tetra-acetate gave dihydroaspertoxin acetate which was converted into dihydroaspertoxin (VIb) by hydrolysis with dilute alkali.

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U2 - 10.1016/S0040-4020(01)90712-4

DO - 10.1016/S0040-4020(01)90712-4

M3 - Article

AN - SCOPUS:49649155853

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SP - 425

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JO - Tetrahedron

JF - Tetrahedron

IS - 2

ER -

The conversion of sterigmatocystin into dihydroaspertoxin

Abstract

ASJC Scopus subject areas

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