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The biosynthesis of showdomycin: Studies with stable isotopes and the determination of principal precursors

  • Heriot-Watt University

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Studies with stable isotopes show that D-ribose and L-glutamic acid are direct biosynthetic precursors of showdomycin (1), with carbons 2-5 and the nitrogen of L-glutamate giving rise to the maleimide ring: L-pyroglutamate may be an intermediate.

Original languageEnglish
Pages (from-to)1515-1517
Number of pages3
JournalJournal of the Chemical Society D: Chemical Communications
Issue number22
DOIs
Publication statusPublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Medicine

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