Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

Sakey Ravindra; Antoine F. Mulaba-Bafubiandi; Vanarchi Rajineekanth; Kokkarachedu Varaprasad; Konduru Mohana Raju

doi:10.1080/03602559.2012.702255

Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

Sakey Ravindra
, Antoine F. Mulaba-Bafubiandi
, Vanarchi Rajineekanth
, Kokkarachedu Varaprasad
, Konduru Mohana Raju

Metallurgy

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N ¹, N ¹-tetram ethylethylene diamine (TMEDA) initiating system and N,N ¹-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.

Original language	English
Pages (from-to)	1355-1360
Number of pages	6
Journal	Polymer - Plastics Technology and Engineering
Volume	51
Issue number	13
DOIs	https://doi.org/10.1080/03602559.2012.702255
Publication status	Published - Sept 2012

Keywords

Drug release
Hydrogel
Surfactant

ASJC Scopus subject areas

Materials Science (miscellaneous)
General Chemical Engineering
Polymers and Plastics
Materials Chemistry

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10.1080/03602559.2012.702255

Cite this

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title = "Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies",

abstract = "In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1, N 1-tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.",

keywords = "Drug release, Hydrogel, Surfactant",

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T1 - Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

AU - Ravindra, Sakey

AU - Mulaba-Bafubiandi, Antoine F.

AU - Rajineekanth, Vanarchi

AU - Varaprasad, Kokkarachedu

AU - Raju, Konduru Mohana

PY - 2012/9

Y1 - 2012/9

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AB - In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1, N 1-tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.

KW - Drug release

KW - Hydrogel

KW - Surfactant

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DO - 10.1080/03602559.2012.702255

M3 - Article

AN - SCOPUS:84867226929

SN - 0360-2559

VL - 51

SP - 1355

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JO - Polymer - Plastics Technology and Engineering

JF - Polymer - Plastics Technology and Engineering

IS - 13

ER -

Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

Abstract

Keywords

ASJC Scopus subject areas

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