Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

Sakey Ravindra, Antoine F. Mulaba-Bafubiandi, Vanarchi Rajineekanth, Kokkarachedu Varaprasad, Konduru Mohana Raju

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1, N 1-tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.

Original languageEnglish
Pages (from-to)1355-1360
Number of pages6
JournalPolymer - Plastics Technology and Engineering
Volume51
Issue number13
DOIs
Publication statusPublished - Sept 2012

Keywords

  • Drug release
  • Hydrogel
  • Surfactant

ASJC Scopus subject areas

  • Materials Science (miscellaneous)
  • General Chemical Engineering
  • Polymers and Plastics
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies'. Together they form a unique fingerprint.

Cite this