Synthesis and binding of peptide T and aminoacyl derivatives to CD4+ lymphocytes

L. H. van den Heever; J. H. Jordaan; I. A. Dubery

doi:10.1016/0020-711X(92)90267-5

Synthesis and binding of peptide T and aminoacyl derivatives to CD₄⁺ lymphocytes

L. H. van den Heever, J. H. Jordaan, I. A. Dubery

Biochemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

1. 1. Peptide T and four other aminoacyl derivatives of this octapeptide were synthesized on solid phase support using the Boc and Fmoc procedures. 2. 2. The octapeptides were modified by chloroacetylation and radiolabelled by halogen exchange with ¹²⁵I. 3. 3. Purified and crude extracts of lymphocytes were used to determine the binding of the octapeptides at different concentrations.

Original language	English
Pages (from-to)	337-339
Number of pages	3
Journal	International Journal of Biochemistry
Volume	24
Issue number	2
DOIs	https://doi.org/10.1016/0020-711X(92)90267-5
Publication status	Published - Feb 1992

ASJC Scopus subject areas

Biochemistry

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10.1016/0020-711X(92)90267-5

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title = "Synthesis and binding of peptide T and aminoacyl derivatives to CD4+ lymphocytes",

abstract = "1. 1. Peptide T and four other aminoacyl derivatives of this octapeptide were synthesized on solid phase support using the Boc and Fmoc procedures. 2. 2. The octapeptides were modified by chloroacetylation and radiolabelled by halogen exchange with 125I. 3. 3. Purified and crude extracts of lymphocytes were used to determine the binding of the octapeptides at different concentrations.",

author = "{van den Heever}, {L. H.} and Jordaan, {J. H.} and Dubery, {I. A.}",

year = "1992",

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doi = "10.1016/0020-711X(92)90267-5",

language = "English",

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journal = "International Journal of Biochemistry",

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publisher = "Elsevier Ltd.",

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T1 - Synthesis and binding of peptide T and aminoacyl derivatives to CD4+ lymphocytes

AU - van den Heever, L. H.

AU - Jordaan, J. H.

AU - Dubery, I. A.

PY - 1992/2

Y1 - 1992/2

N2 - 1. 1. Peptide T and four other aminoacyl derivatives of this octapeptide were synthesized on solid phase support using the Boc and Fmoc procedures. 2. 2. The octapeptides were modified by chloroacetylation and radiolabelled by halogen exchange with 125I. 3. 3. Purified and crude extracts of lymphocytes were used to determine the binding of the octapeptides at different concentrations.

AB - 1. 1. Peptide T and four other aminoacyl derivatives of this octapeptide were synthesized on solid phase support using the Boc and Fmoc procedures. 2. 2. The octapeptides were modified by chloroacetylation and radiolabelled by halogen exchange with 125I. 3. 3. Purified and crude extracts of lymphocytes were used to determine the binding of the octapeptides at different concentrations.

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U2 - 10.1016/0020-711X(92)90267-5

DO - 10.1016/0020-711X(92)90267-5

M3 - Article

C2 - 1346383

AN - SCOPUS:0026808242

SN - 0020-711X

VL - 24

SP - 337

EP - 339

JO - International Journal of Biochemistry

JF - International Journal of Biochemistry

IS - 2

ER -

Synthesis and binding of peptide T and aminoacyl derivatives to CD₄⁺ lymphocytes

Abstract

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