Swelling and drug release kinetics of biopolymer in situ-forming hydrogels for ophthalmic drug delivery

Jonathan Tersur Orasugh; Dipankar Chattopadhyay; Suprakas Sinha Ray; Anjan Adhikari

doi:10.1016/B978-0-323-99156-8.00019-8

Swelling and drug release kinetics of biopolymer in situ-forming hydrogels for ophthalmic drug delivery

Jonathan Tersur Orasugh, Dipankar Chattopadhyay, Suprakas Sinha Ray, Anjan Adhikari

Chemical Sciences

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

This chapter delves into the vital aspects of biopolymer-based in situ-forming hydrogels designed for ophthalmic drug delivery (DD). Focusing on swelling behavior and drug release (DR) kinetics, it explores the key factors influencing these processes. By elucidating the mechanisms governing swelling and DR, this chapter provides valuable insights for researchers and practitioners aiming to enhance DD to the eye. The findings presented here pave the way for the development of more effective and patient-friendly ophthalmic DD systems.

Original language	English
Title of host publication	Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery
Publisher	Elsevier
Pages	299-306
Number of pages	8
ISBN (Electronic)	9780323991568
ISBN (Print)	9780323993593
DOIs	https://doi.org/10.1016/B978-0-323-99156-8.00019-8
Publication status	Published - 1 Jan 2024

Keywords

Biopolymers
Controlled release
Drug release kinetics
In situ-forming hydrogels
Ophthalmic drug delivery
Swelling

ASJC Scopus subject areas

General Engineering
General Materials Science

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10.1016/B978-0-323-99156-8.00019-8

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abstract = "This chapter delves into the vital aspects of biopolymer-based in situ-forming hydrogels designed for ophthalmic drug delivery (DD). Focusing on swelling behavior and drug release (DR) kinetics, it explores the key factors influencing these processes. By elucidating the mechanisms governing swelling and DR, this chapter provides valuable insights for researchers and practitioners aiming to enhance DD to the eye. The findings presented here pave the way for the development of more effective and patient-friendly ophthalmic DD systems.",

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AU - Adhikari, Anjan

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AB - This chapter delves into the vital aspects of biopolymer-based in situ-forming hydrogels designed for ophthalmic drug delivery (DD). Focusing on swelling behavior and drug release (DR) kinetics, it explores the key factors influencing these processes. By elucidating the mechanisms governing swelling and DR, this chapter provides valuable insights for researchers and practitioners aiming to enhance DD to the eye. The findings presented here pave the way for the development of more effective and patient-friendly ophthalmic DD systems.

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KW - Controlled release

KW - Drug release kinetics

KW - In situ-forming hydrogels

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KW - Swelling

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BT - Stimuli-Responsive Hydrogels for Ophthalmic Drug Delivery

PB - Elsevier

ER -

Swelling and drug release kinetics of biopolymer in situ-forming hydrogels for ophthalmic drug delivery

Abstract

Keywords

ASJC Scopus subject areas

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