Stereospecific synthesis of intermediates for 11-aza-ll-deoxy and 11—azaprostaglandin analogues from l—arabinose

G. H. Verdoorn; C. W. Holzapfel; D. H. Braithwaite; A. E. Platen

doi:10.1080/00397919208021312

Stereospecific synthesis of intermediates for 11-aza-ll-deoxy and 11—azaprostaglandin analogues from l—arabinose

G. H. Verdoorn, C. W. Holzapfel, D. H. Braithwaite, A. E. Platen

Chemical Sciences

University of Johannesburg

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The syntheses of chiral synthons for 11—aza—11—deoxy and 11—azaprostanoids are described. The key intermediate in both routes was 5—O-benzoyl—3 C- (carboxymethyl—2, 3—^lactone)—3—deoxy—a-L-lyxo— furanose which is readily available from L—arabinose.

Original language	English
Pages (from-to)	1813-1829
Number of pages	17
Journal	Synthetic Communications
Volume	22
Issue number	13
DOIs	https://doi.org/10.1080/00397919208021312
Publication status	Published - 1 Jul 1992

ASJC Scopus subject areas

Organic Chemistry

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10.1080/00397919208021312

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title = "Stereospecific synthesis of intermediates for 11-aza-ll-deoxy and 11—azaprostaglandin analogues from l—arabinose",

abstract = "The syntheses of chiral synthons for 11—aza—11—deoxy and 11—azaprostanoids are described. The key intermediate in both routes was 5—O-benzoyl—3 C- (carboxymethyl—2, 3—^lactone)—3—deoxy—a-L-lyxo— furanose which is readily available from L—arabinose.",

author = "Verdoorn, {G. H.} and Holzapfel, {C. W.} and Braithwaite, {D. H.} and Platen, {A. E.}",

year = "1992",

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T1 - Stereospecific synthesis of intermediates for 11-aza-ll-deoxy and 11—azaprostaglandin analogues from l—arabinose

AU - Verdoorn, G. H.

AU - Holzapfel, C. W.

AU - Braithwaite, D. H.

AU - Platen, A. E.

PY - 1992/7/1

Y1 - 1992/7/1

N2 - The syntheses of chiral synthons for 11—aza—11—deoxy and 11—azaprostanoids are described. The key intermediate in both routes was 5—O-benzoyl—3 C- (carboxymethyl—2, 3—^lactone)—3—deoxy—a-L-lyxo— furanose which is readily available from L—arabinose.

AB - The syntheses of chiral synthons for 11—aza—11—deoxy and 11—azaprostanoids are described. The key intermediate in both routes was 5—O-benzoyl—3 C- (carboxymethyl—2, 3—^lactone)—3—deoxy—a-L-lyxo— furanose which is readily available from L—arabinose.

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DO - 10.1080/00397919208021312

M3 - Article

AN - SCOPUS:0026742396

SN - 0039-7911

VL - 22

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JO - Synthetic Communications

JF - Synthetic Communications

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ER -

Stereospecific synthesis of intermediates for 11-aza-ll-deoxy and 11—azaprostaglandin analogues from l—arabinose

Abstract

ASJC Scopus subject areas

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