Stereoselective SmI2-mediated conversion of carbohydrates into cyclopentanols

J. J.Cronjé Grové, Cedric W. Holzapfel, D. Bradley G. Williams

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

Carbohydrate derivatives were employed as precursors in the synthesis of stereodefined cyclopentanols. This rapid conversion was effected by a zinc-assisted Grob-fragmentation, followed by a stereocontrolled SmI2-mediated cyclisation.

Original languageEnglish
Pages (from-to)1305-1308
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number8
DOIs
Publication statusPublished - 19 Feb 1996

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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