Starches-blended ionotropically cross-linked biopolymeric matrices for sustained drug release

T. C. Mokhena, M. J. Mochane, K. P. Matabola, S. S. Ray, A. Mtibe, M. F. Bambo, S. A. Modise, T. E. Motsoeneng

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Starches drew more attention to drug delivery systems. This results from their distinctive characteristics, which include inexpressiveness, abundant availability, renewability, biodegradability, and biocompatibility. For some time now, many sources have been investigated to isolate starch to formulate sustained drug-release systems. In this respect, starch is blended with other ionic polymeric materials with or without a cross-linking agent through the ionotropic gelation method. This chapter discusses the use of starch-based formulations prepared via the ionotropic gelation technique as sustained and prolonged drug delivery systems.

Original languageEnglish
Title of host publicationIonotropic Cross-Linking of Biopolymers
Subtitle of host publicationApplications in Drug Delivery
PublisherElsevier
Pages275-297
Number of pages23
ISBN (Electronic)9780323961165
ISBN (Print)9780323996709
DOIs
Publication statusPublished - 1 Jan 2024
Externally publishedYes

Keywords

  • biopolymer blends
  • drug delivery systems
  • ionotropic gelation
  • Starch

ASJC Scopus subject areas

  • General Engineering
  • General Materials Science

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