Simple green synthesis of amino acid functionalised CdTe/CdSe/ZnSe core-multi shell with improved cell viability for cellular imaging

Vuyelwa Ncapayi; Sundararajan Parani; Sandile P. Songca; Tetsuya Kodama; Oluwatobi S. Oluwafemi

doi:10.1016/j.matlet.2016.12.006

Simple green synthesis of amino acid functionalised CdTe/CdSe/ZnSe core-multi shell with improved cell viability for cellular imaging

Vuyelwa Ncapayi, Sundararajan Parani, Sandile P. Songca, Tetsuya Kodama, Oluwatobi S. Oluwafemi

Chemical Sciences

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

We herein report a simple, economical and green synthesis of highly fluorescent, water soluble and stable arginine functionalised CdTe/CdSe/ZnSe multi core-shell nanoparticles (NPs) with enhanced cell viability for cellular imaging. The synthesis of the CdTe/CdSe/ZnSe NPs was carried out under ambient conditions in the absence of an inert environment. The as-prepared NPs were characterised using UV–vis absorption and photoluminescence (PL) spectroscopy, energy dispersive spectroscopy (EDS) and high resolution transmission electron microscopy (HRTEM). The optical analyses showed an enhancement in the fluorescent intensity after the functionalisation with improved optical properties. The functionalised NPs (F-NPs) displayed higher cell viability compared to the bare NPs when investigated on KM-Luc/GFP cell line at different concentrations. The fluorescent image indicated that the as-synthesised functionalised NPs were taken up by the cells.

Original language	English
Pages (from-to)	168-171
Number of pages	4
Journal	Materials Letters
Volume	189
DOIs	https://doi.org/10.1016/j.matlet.2016.12.006
Publication status	Published - 15 Feb 2017

Keywords

CdTe/CdSe/ZnSe
Functionalisation
KM-Luc/GFP cell, arginine
Nanoparticles

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1016/j.matlet.2016.12.006

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title = "Simple green synthesis of amino acid functionalised CdTe/CdSe/ZnSe core-multi shell with improved cell viability for cellular imaging",

abstract = "We herein report a simple, economical and green synthesis of highly fluorescent, water soluble and stable arginine functionalised CdTe/CdSe/ZnSe multi core-shell nanoparticles (NPs) with enhanced cell viability for cellular imaging. The synthesis of the CdTe/CdSe/ZnSe NPs was carried out under ambient conditions in the absence of an inert environment. The as-prepared NPs were characterised using UV–vis absorption and photoluminescence (PL) spectroscopy, energy dispersive spectroscopy (EDS) and high resolution transmission electron microscopy (HRTEM). The optical analyses showed an enhancement in the fluorescent intensity after the functionalisation with improved optical properties. The functionalised NPs (F-NPs) displayed higher cell viability compared to the bare NPs when investigated on KM-Luc/GFP cell line at different concentrations. The fluorescent image indicated that the as-synthesised functionalised NPs were taken up by the cells.",

keywords = "CdTe/CdSe/ZnSe, Functionalisation, KM-Luc/GFP cell, arginine, Nanoparticles",

author = "Vuyelwa Ncapayi and Sundararajan Parani and Songca, {Sandile P.} and Tetsuya Kodama and Oluwafemi, {Oluwatobi S.}",

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doi = "10.1016/j.matlet.2016.12.006",

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journal = "Materials Letters",

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T1 - Simple green synthesis of amino acid functionalised CdTe/CdSe/ZnSe core-multi shell with improved cell viability for cellular imaging

AU - Ncapayi, Vuyelwa

AU - Parani, Sundararajan

AU - Songca, Sandile P.

AU - Kodama, Tetsuya

AU - Oluwafemi, Oluwatobi S.

PY - 2017/2/15

Y1 - 2017/2/15

N2 - We herein report a simple, economical and green synthesis of highly fluorescent, water soluble and stable arginine functionalised CdTe/CdSe/ZnSe multi core-shell nanoparticles (NPs) with enhanced cell viability for cellular imaging. The synthesis of the CdTe/CdSe/ZnSe NPs was carried out under ambient conditions in the absence of an inert environment. The as-prepared NPs were characterised using UV–vis absorption and photoluminescence (PL) spectroscopy, energy dispersive spectroscopy (EDS) and high resolution transmission electron microscopy (HRTEM). The optical analyses showed an enhancement in the fluorescent intensity after the functionalisation with improved optical properties. The functionalised NPs (F-NPs) displayed higher cell viability compared to the bare NPs when investigated on KM-Luc/GFP cell line at different concentrations. The fluorescent image indicated that the as-synthesised functionalised NPs were taken up by the cells.

AB - We herein report a simple, economical and green synthesis of highly fluorescent, water soluble and stable arginine functionalised CdTe/CdSe/ZnSe multi core-shell nanoparticles (NPs) with enhanced cell viability for cellular imaging. The synthesis of the CdTe/CdSe/ZnSe NPs was carried out under ambient conditions in the absence of an inert environment. The as-prepared NPs were characterised using UV–vis absorption and photoluminescence (PL) spectroscopy, energy dispersive spectroscopy (EDS) and high resolution transmission electron microscopy (HRTEM). The optical analyses showed an enhancement in the fluorescent intensity after the functionalisation with improved optical properties. The functionalised NPs (F-NPs) displayed higher cell viability compared to the bare NPs when investigated on KM-Luc/GFP cell line at different concentrations. The fluorescent image indicated that the as-synthesised functionalised NPs were taken up by the cells.

KW - CdTe/CdSe/ZnSe

KW - Functionalisation

KW - KM-Luc/GFP cell, arginine

KW - Nanoparticles

UR - http://www.scopus.com/inward/record.url?scp=85004019882&partnerID=8YFLogxK

U2 - 10.1016/j.matlet.2016.12.006

DO - 10.1016/j.matlet.2016.12.006

M3 - Article

AN - SCOPUS:85004019882

SN - 0167-577X

VL - 189

SP - 168

EP - 171

JO - Materials Letters

JF - Materials Letters

ER -

Simple green synthesis of amino acid functionalised CdTe/CdSe/ZnSe core-multi shell with improved cell viability for cellular imaging

Abstract

Keywords

ASJC Scopus subject areas

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