Silver(I) Bromide Phosphines Induce Mitochondrial-Mediated Apoptosis in Malignant Human Colorectal Cells

Keyphrases

• 1H-13C 33%
• Alamar Blue 33%
• Anticancer Properties 33%
• Anticancer Therapeutics 33%
• Antimicrobial 33%
• Antiproliferative Agents 33%
• Apoptosis 33%
• Base Metals 33%
• Cancer Types 33%
• CDDP 33%
• Cell Proliferation 33%
• Colon Cancer 33%
• Colorectal Cancer Cells 33%
• Colorectal Cancer Prevention 33%
• Colorectal Cells 100%
• Complex Potential 33%
• Current Therapies 33%
• Dimethylamino 33%
• Diphenyl-2-pyridylphosphine 33%
• Elemental Analysis 33%
• Emerging Resistance 33%
• Flow Cytometric 33%
• Flow Cytometry Analysis 33%
• High Efficacy 33%
• HT-29 66%
• Human Embryonic Kidney 293 (HEK293) 33%
• IC50 100%
• Infrared Spectroscopy 33%
• Inhibitory Effect 33%
• Membrane Blebbing 33%
• Mitochondria 33%
• Mitochondria-mediated Apoptosis 100%
• Mitochondrial Alterations 33%
• Mitochondrial Depolarization 33%
• Morphological Changes 66%
• Nonmalignant 33%
• Novel Metals 33%
• Nuclear Magnetic Resonance 33%
• Phosphine 100%
• Proliferation Assay 33%
• PS Externalization 33%
• Reactive Oxygen Species 33%
• Regulated Cell Death 33%
• Selective Treatment 33%
• Silver Ions 66%
• Silver(I) Bromide 100%
• Silver(I) Phosphine Complexes 33%
• Superior Selectivity 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Antiinfective Agent 20%
• Biphenyl 20%
• Carbon 13 20%
• Colon Carcinoma 20%
• Colorectal Carcinoma 40%
• Elemental Analysis 20%
• IC50 60%
• Infrared Spectroscopy 20%
• Malignant Neoplasm 60%
• Phosphine 20%
• Phosphine Derivative 100%
• Phosphorus 31 20%
• Reactive Oxygen Metabolite 20%
• Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase (Ubiquinone) 100%

Chemistry

• 13C{1H}-NMR Spectroscopy 33%
• Antineoplastic Agent 33%
• Antiproliferative 33%
• Biphenyl 33%
• Cell Death 33%
• Elemental Analysis 33%
• IC50 100%
• Infrared Spectroscopy 33%
• Phosphine 33%
• Reactive Oxygen Metabolite 33%
• Silver 33%