Abstract
Acute liver injury (ALI) is a critical and fatal disorder associated with excessive Alt-hough considerable advances have been made in the early diagnosis and treatment of breast cancer, it is still one of the major causes of global cancer-related death in women over the last several decades. Phytochemicals have been shown to be promising agents in the prevention and treatment of breast cancer. Resveratrol is an important plant-derived polyphenolic compound with a variety of potent biological activities. It has been suggested that resveratrol can be used to prevent and treat various types of cancer, including breast cancer. Resveratrol can affect nu-merous signaling pathways in vitro, leading to the induction of cell cycle arrest and apoptosis, suppression of proliferation, reduction of inflammatory responses, and the inhibition of angio-genesis and metastasis. Nevertheless, studies of resveratrol in animal models of breast cancer have so far been disappointing.
| Original language | English |
|---|---|
| Pages (from-to) | 346-361 |
| Number of pages | 16 |
| Journal | Current Molecular Pharmacology |
| Volume | 16 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2023 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Breast cancer
- cancer therapy
- chemotherapy
- phytochemicals
- resveratrol
- signaling pathways
ASJC Scopus subject areas
- Molecular Medicine
- Pharmacology
- Drug Discovery
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