Regioselective oxidation of carbohydrate triols: facile synthesis of 2,3-O-isopropylidene-β-d-threo-hexo-2,4-diulo-pyranose and 1,2-O-isopropylidene-β-d-threo-hexo-2,5,diulo-pyranose

Laetitia den Drijver, Cedric W. Holzapfel, Johannes M. Koekemoer, Gert J. Kruger, Martha S. van Dyk

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

Stannylation of 2,3-O-isopropylidene-β-d-fructopyranose with dibutyltin oxide followed by brominolysis afforded 2,3-O-isopropylidene-β-d-threo-hexo-2,4-diulopyranose, which was characterised as its oxime. Brominolysis of the O-dibutylstannylene derivative of 1,2-O-isopylidene-β-d-fructopyranose furnished 1,2-O-isopropylidene-β-d-threo-hexo-2,5-diulopyranose, which was characterised as the corresponding O-methyloxime diacetate.

Original languageEnglish
Pages (from-to)141-150
Number of pages10
JournalCarbohydrate Research
Volume155
Issue numberC
DOIs
Publication statusPublished - 1 Nov 1986

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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