Rational synthesis of rare-earth lanthanum molybdate covered reduced graphene oxide nanocomposites for the voltammetric detection of Moxifloxacin hydrochloride

Muthumariappan Akilarasan, Elayappan Tamilalagan, Shen Ming Chen, Selvarasu Maheshwaran, Chih Hsuan Fan, Mohamed A. Habila, Mika Sillanpää

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

Recently, perovskite structure-based metal oxide nanomaterials and their composites opted for electrocatalyst because of its excellent conductivity, unique, and favored electronic structure. In this attempt, herein we prepared the rare earth mixed metal molybdate covered reduced graphene oxide La2(MoO4)3@rGO nanocomposites by a simple hydrothermal method for the sensitive detection of Moxifloxacin hydrochloride (MOF) in pharmaceutical and human urine samples. The various physicochemical analysis such as SEM, TEM, XRD and Raman spectroscopy confirms the successful formation of (La2(MoO4)3@rGO) nanocomposites. Furthermore, the electroanalytical performance of La2(MoO4)3@rGO modified glassy carbon electrode (La2(MoO4)3@rGO/GCE) was analyzed using the cyclic voltammetry (CV) and differential pulse voltammetry (DPV) which shows excellent results with a wide range of 1.0 × 10−8 M to 6.0 × 10−4 M and the detection limit of 2.84 × 10−9 M towards the MOF detection. Furthermore, the developed sensor expressed good selectivity, repeatability, stability and reproducibility. Finally, the real sample analysis of the developed sensor was tested in the MOF tablets and human urine samples, which shows the appreciable recoveries.

Original languageEnglish
Article number108145
JournalBioelectrochemistry
Volume146
DOIs
Publication statusPublished - Aug 2022
Externally publishedYes

Keywords

  • Binary-metal oxide
  • Drug analysis
  • Electrochemical sensor
  • La(MoO)@rGO nanocomposites
  • Moxifloxacin hydrochloride sensor

ASJC Scopus subject areas

  • Biophysics
  • Physical and Theoretical Chemistry
  • Electrochemistry

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