Preconditioning with Photobiomodulation in Neuronal Cells and the Brain

This chapter explores the concept of preconditioning with photobiomodulation (PBM) in the context of neuronal cells and the brain, focusing on its potential to enhance resilience against various stressors and promote neuroprotection. Section 1 introduces the idea of preconditioning, explaining its significance in the field of PBM and how it can be used to prime neuronal cells and the brain for subsequent challenges or insults. Section 2 delves into in vitro studies on preconditioning with PBM, highlighting experimental evidence of its effects on neuronal cells. This section presents various studies that demonstrate the benefits of PBM preconditioning, such as enhanced cell survival, reduced oxidative stress, and increased resistance to apoptosis in the face of various stressors. Section 3 examines in vivo studies on preconditioning with PBM in the context of the brain. This section discusses the application of preconditioning in animal models and its potential to protect the brain against various insults, such as ischemia, neurodegeneration, and traumatic brain injury. The discussion includes insights into the underlying molecular and cellular mechanisms that contribute to the neuroprotective effects of PBM preconditioning.