Phototherapy combined with carbon nanomaterials (1d and 2d) and their applications in cancer therapy

Prabhavathi Sundaram, Heidi Abrahamse

Research output: Contribution to journalReview articlepeer-review

33 Citations (Scopus)

Abstract

Carbon‐based materials have attracted research interest worldwide due to their physical and chemical properties and wide surface area, rendering them excellent carrier molecules. They are widely used in biological applications like antimicrobial activity, cancer diagnosis, bio‐imaging, targeting, drug delivery, biosensors, tissue engineering, dental care, and skin care. Carbon‐based nanomaterials like carbon nanotubes and graphene have drawn more attention in the field of phototherapy due to their unique properties such as thermal conductivity, large surface area, and electrical properties. Phototherapy is a promising next‐generation therapeutic modality for many modern medical conditions that include cancer diagnosis, targeting, and treatment. Phototherapy involves the major administration of photosensitizers (PSs), which absorb light sources and emit reactive oxygen species under cellular environments. Several types of nontoxic PSs are functionalized on carbon‐based nanomaterials and have numerous advantages in cancer therapy. In this review, we discuss the potential role and combined effect of phototherapy and carbon nanomaterials, the mechanism and functionalization of PSs on nanomaterials, and their promising advantages in cancer therapy.

Original languageEnglish
Article number4830
Pages (from-to)1-22
Number of pages22
JournalMaterials
Volume13
Issue number21
DOIs
Publication statusPublished - 1 Nov 2020

Keywords

  • Cancer
  • Carbon nanotubes
  • Graphene
  • Photodynamic therapy
  • Photosensitizers
  • Phototherapy

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics

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