Photorhabdus sp. ETL antimicrobial properties and characterization of its secondary metabolites by gas chromatography–mass spectrometry

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17 Citations (Scopus)

Abstract

Entomopathogenic nematodes (EPNs) are known to be highly pathogenic to insect pests, due to their associated symbiotic bacteria, which produce virulence factors, exo-enzymes and other harmful secondary metabolites to conquer, kill, and degrade their insect hosts. However, these properties are not fully characterized. This study reports on the antimicrobial activities of Photorhabdus sp. strain ETL, symbiotically associated to an insect pathogenic nematode, Heterorhabditis zealandica, against human pathogenic bacteria and toxigenic fungi, as well as the non-targeted profiling of its secondary metabolites (SMs) using gas chromatography coupled to high-resolution time-offlight mass spectrometry. Fatty acids including 3-eicosene, (E)-; 5-eicosene, (E)-; eicosene; 9-octade-cenamide; undecanoic acid with shown antimicrobial activities were detected. This provided more insight on the composition and bioactivities of SMs produced by the Photorhabdus sp.

Original languageEnglish
Article number787
JournalLife
Volume11
Issue number8
DOIs
Publication statusPublished - Aug 2021

Keywords

  • Antimicrobial properties
  • Gas chromatography–mass spectrometry
  • Photorhabdus heterorhabditis strain ETL
  • Secondary metabolites

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • General Biochemistry,Genetics and Molecular Biology
  • Space and Planetary Science
  • Paleontology

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