Abstract
Photodynamic therapy (PDT) is the most interdisciplinary therapeutic approach in modern biomedical research. PDT consists of concomitant application of three important agents: light, photosensitizers (PS), and O2. PDT dosimetry has been adopted from conventions developed for anticancer radiation therapies. The significant advances and developments in light-based strategies for achieving selective-enhanced PS concentration on target tissues play a major role in PDT. Clinicians are increasingly initiating clinical trials of PDT and utilizing PDT in their own practices. Dermatology may be the mature clinical specialty for PDT usage, but oncology, dentistry, and ophthalmology are close runners up. Infectious disease is perhaps the area that is thought to have the most potential for future growth, while immunology is considered to be a largely unexplored area in which PDT may possibly lead to a cure for advanced metastatic cancer if the factors that govern the activation of the immune response can be fully understood.
| Original language | English |
|---|---|
| Title of host publication | Biomedical Photonics, Spectroscopy, and Microscopy |
| Publisher | wiley |
| Pages | 413-467 |
| Number of pages | 55 |
| Volume | 4 |
| ISBN (Electronic) | 9781119011804 |
| ISBN (Print) | 9781118225554 |
| DOIs | |
| Publication status | Published - 27 Feb 2015 |
| Externally published | Yes |
Keywords
- Dermatology
- Immune system
- Infectious disease
- Light dosimetry
- Light-based strategies
- Oncology
- Ophthalmology
- Photodynamic therapy (PDT)
- Photosensitizers (PS)
ASJC Scopus subject areas
- General Engineering
- General Physics and Astronomy
