TY - CHAP
T1 - Photobiomodulation in Neuronal Cell Cultures
AU - Salehpour, Farzad
AU - Sadigh-Eteghad, Saeed
AU - Mahmoudi, Javad
AU - Kamari, Farzin
AU - Cassano, Paolo
AU - Hamblin, Michael Richard
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.
PY - 2023
Y1 - 2023
N2 - This chapter delves into the application of photobiomodulation (PBM) in neuronal cell cultures, focusing on the importance of in vitro studies and the various cellular mechanisms affected by this treatment approach. Section 1 discusses the importance of in vitro studies, highlighting their value in providing controlled environments for the investigation of PBM’s effects on neuronal cells. In vitro models allow researchers to isolate specific factors, test various treatment parameters, and elucidate underlying cellular and molecular mechanisms. Section 2 presents an overview of in vitro PBM studies, organized into several subsections discussing the different cellular mechanisms impacted by PBM. These mechanisms include cytochrome c oxidase activity, nitric oxide modulation, reactive oxygen species modulation, mitochondrial membrane potential regulation, and Ca2+ regulation. Overall, this chapter provides a comprehensive understanding of PBM’s effects on neuronal cell cultures, emphasizing the importance of in vitro studies for elucidating the cellular and molecular mechanisms underlying this therapeutic approach.
AB - This chapter delves into the application of photobiomodulation (PBM) in neuronal cell cultures, focusing on the importance of in vitro studies and the various cellular mechanisms affected by this treatment approach. Section 1 discusses the importance of in vitro studies, highlighting their value in providing controlled environments for the investigation of PBM’s effects on neuronal cells. In vitro models allow researchers to isolate specific factors, test various treatment parameters, and elucidate underlying cellular and molecular mechanisms. Section 2 presents an overview of in vitro PBM studies, organized into several subsections discussing the different cellular mechanisms impacted by PBM. These mechanisms include cytochrome c oxidase activity, nitric oxide modulation, reactive oxygen species modulation, mitochondrial membrane potential regulation, and Ca2+ regulation. Overall, this chapter provides a comprehensive understanding of PBM’s effects on neuronal cell cultures, emphasizing the importance of in vitro studies for elucidating the cellular and molecular mechanisms underlying this therapeutic approach.
UR - http://www.scopus.com/inward/record.url?scp=85169015798&partnerID=8YFLogxK
U2 - 10.1007/978-3-031-36231-6_8
DO - 10.1007/978-3-031-36231-6_8
M3 - Chapter
AN - SCOPUS:85169015798
T3 - Synthesis Lectures on Biomedical Engineering
SP - 143
EP - 163
BT - Synthesis Lectures on Biomedical Engineering
PB - Springer Nature
ER -