Photobiomodulation and Light Therapy in Oncology: Mechanisms and Positive or Negative Effects on Cancer

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Photobiomodulation (PBM) is now over 50 years old and has recently started to gain more widespread acceptance within the medical community. Alleviation of the side effects of cancer therapy has so far been one of the most impressive applications of PBM and the focus of this chapter. I will cover the mechanism of action and ask whether the effects of PBM on cancer cells and tumors is more likely to be positive or negative. There are some ways that PBM could actually attack the cancer either directly or indirectly, or in combination with other cytotoxic therapies. Finally, I will summarize the clinical applications of PBM against such side effects as oral mucositis, radiation dermatitis, dysphagia, hyposalivation and xerostomia, taste alterations, trismus, head and neck lymphedema, and voice and speech alterations.

Original languageEnglish
Title of host publicationOrofacial Supportive Care in Cancer
Subtitle of host publicationA Contemporary Oral Oncology Perspective
PublisherSpringer International Publishing
Number of pages32
ISBN (Electronic)9783030865108
ISBN (Print)9783030865092
Publication statusPublished - 1 Jan 2022


  • Anti-cancer effects
  • Cancer therapy side effects
  • Dysphagia
  • Head and neck lymphedema
  • Hyposalivation and xerostomia
  • Oral mucositis
  • Photobiomodulation
  • Radiation dermatitis
  • Taste alterations
  • Trismus
  • Voice and speech alterations

ASJC Scopus subject areas

  • General Dentistry
  • General Medicine


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