Performance of the first fourth-generation rapid human immunodeficiency virus test in children

Kapila Bhowan; Gayle G. Sherman

doi:10.1097/INF.0b013e31827b4775

Performance of the first fourth-generation rapid human immunodeficiency virus test in children

Kapila Bhowan, Gayle G. Sherman

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Diagnosing HIV infection in infants by p24 antigen detection at point of care is likely to reduce infant morbidity and mortality. A fourth-generation rapid test evaluated on 202 stored samples from children of known age and clinical presentation demonstrated a sensitivity of <2% for detecting p24 antigen in 61 HIV-infected infants and demonstrated 100% sensitivity and specificity for detecting HIV antibodies in infants aged 6 months and younger.

Original language	English
Pages (from-to)	486-488
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	32
Issue number	5
DOIs	https://doi.org/10.1097/INF.0b013e31827b4775
Publication status	Published - May 2013
Externally published	Yes

Keywords

Children
Fourth generation
Human immunodeficiency virus
P24 antigen
Rapid test

ASJC Scopus subject areas

Pediatrics, Perinatology and Child Health
Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/INF.0b013e31827b4775

Cite this

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title = "Performance of the first fourth-generation rapid human immunodeficiency virus test in children",

abstract = "Diagnosing HIV infection in infants by p24 antigen detection at point of care is likely to reduce infant morbidity and mortality. A fourth-generation rapid test evaluated on 202 stored samples from children of known age and clinical presentation demonstrated a sensitivity of <2% for detecting p24 antigen in 61 HIV-infected infants and demonstrated 100% sensitivity and specificity for detecting HIV antibodies in infants aged 6 months and younger.",

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AU - Sherman, Gayle G.

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AB - Diagnosing HIV infection in infants by p24 antigen detection at point of care is likely to reduce infant morbidity and mortality. A fourth-generation rapid test evaluated on 202 stored samples from children of known age and clinical presentation demonstrated a sensitivity of <2% for detecting p24 antigen in 61 HIV-infected infants and demonstrated 100% sensitivity and specificity for detecting HIV antibodies in infants aged 6 months and younger.

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KW - Fourth generation

KW - Human immunodeficiency virus

KW - P24 antigen

KW - Rapid test

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M3 - Article

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Performance of the first fourth-generation rapid human immunodeficiency virus test in children

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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