On the biosynthesis of cyclopiazonic acid

C. W. Holzapfel; D. C. Wilkins

doi:10.1016/S0031-9422(00)94050-0

On the biosynthesis of cyclopiazonic acid

C. W. Holzapfel, D. C. Wilkins

Council for Scientific and Industrial Research

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

The biosynthesis of cyclopiazonic acid (I) was studied in Penicillium cyclopium Westling by radiolabelling experiments. Evidence is presented that cyclopiazonic acid is derived from tryptophan, a C₅-unit formed from mevalonic acid and two molecules of acetic acid. Bissecodehydrocyclopiazonic acid (X) is a direct precursor of cyclopiazonic acid.

Original language	English
Pages (from-to)	351-358
Number of pages	8
Journal	Phytochemistry
Volume	10
Issue number	2
DOIs	https://doi.org/10.1016/S0031-9422(00)94050-0
Publication status	Published - Feb 1971
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/S0031-9422(00)94050-0

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abstract = "The biosynthesis of cyclopiazonic acid (I) was studied in Penicillium cyclopium Westling by radiolabelling experiments. Evidence is presented that cyclopiazonic acid is derived from tryptophan, a C5-unit formed from mevalonic acid and two molecules of acetic acid. Bissecodehydrocyclopiazonic acid (X) is a direct precursor of cyclopiazonic acid.",

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AU - Wilkins, D. C.

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AB - The biosynthesis of cyclopiazonic acid (I) was studied in Penicillium cyclopium Westling by radiolabelling experiments. Evidence is presented that cyclopiazonic acid is derived from tryptophan, a C5-unit formed from mevalonic acid and two molecules of acetic acid. Bissecodehydrocyclopiazonic acid (X) is a direct precursor of cyclopiazonic acid.

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DO - 10.1016/S0031-9422(00)94050-0

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JO - Phytochemistry

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On the biosynthesis of cyclopiazonic acid

Abstract

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