On the biosynthesis of cyclopiazonic acid

C. W. Holzapfel, D. C. Wilkins

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)


The biosynthesis of cyclopiazonic acid (I) was studied in Penicillium cyclopium Westling by radiolabelling experiments. Evidence is presented that cyclopiazonic acid is derived from tryptophan, a C5-unit formed from mevalonic acid and two molecules of acetic acid. Bissecodehydrocyclopiazonic acid (X) is a direct precursor of cyclopiazonic acid.

Original languageEnglish
Pages (from-to)351-358
Number of pages8
Issue number2
Publication statusPublished - Feb 1971
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Plant Science
  • Horticulture


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