TY - JOUR
T1 - Non-Coding RNAs and Brain Tumors
T2 - Insights Into Their Roles in Apoptosis
AU - Tamtaji, Omid Reza
AU - Derakhshan, Maryam
AU - Rashidi Noshabad, Fatemeh Zahra
AU - Razaviyan, Javad
AU - Hadavi, Razie
AU - Jafarpour, Hamed
AU - Jafari, Ameneh
AU - Rajabi, Ali
AU - Hamblin, Michael R.
AU - Mahabady, Mahmood Khaksary
AU - Taghizadieh, Mohammad
AU - Mirzaei, Hamed
N1 - Publisher Copyright:
Copyright © 2022 Tamtaji, Derakhshan, Rashidi Noshabad, Razaviyan, Hadavi, Jafarpour, Jafari, Rajabi, Hamblin, Mahabady, Taghizadieh and Mirzaei.
PY - 2022/1/17
Y1 - 2022/1/17
N2 - A major terrifying ailment afflicting the humans throughout the world is brain tumor, which causes a lot of mortality among pediatric and adult solid tumors. Several major barriers to the treatment and diagnosis of the brain tumors are the specific micro-environmental and cell-intrinsic features of neural tissues. Absence of the nutrients and hypoxia trigger the cells’ mortality in the core of the tumors of humans’ brains: however, type of the cells’ mortality, including apoptosis or necrosis, has been not found obviously. Current studies have emphasized the non-coding RNAs (ncRNAs) since their crucial impacts on carcinogenesis have been discovered. Several investigations suggest the essential contribution of such molecules in the development of brain tumors and the respective roles in apoptosis. Herein, we summarize the apoptosis-related non-coding RNAs in brain tumors.
AB - A major terrifying ailment afflicting the humans throughout the world is brain tumor, which causes a lot of mortality among pediatric and adult solid tumors. Several major barriers to the treatment and diagnosis of the brain tumors are the specific micro-environmental and cell-intrinsic features of neural tissues. Absence of the nutrients and hypoxia trigger the cells’ mortality in the core of the tumors of humans’ brains: however, type of the cells’ mortality, including apoptosis or necrosis, has been not found obviously. Current studies have emphasized the non-coding RNAs (ncRNAs) since their crucial impacts on carcinogenesis have been discovered. Several investigations suggest the essential contribution of such molecules in the development of brain tumors and the respective roles in apoptosis. Herein, we summarize the apoptosis-related non-coding RNAs in brain tumors.
KW - apoptosis
KW - brain tumors
KW - long non-coding (lnc) RNA
KW - microRNA
KW - non-coding RNAs
UR - http://www.scopus.com/inward/record.url?scp=85123797377&partnerID=8YFLogxK
U2 - 10.3389/fcell.2021.792185
DO - 10.3389/fcell.2021.792185
M3 - Review article
AN - SCOPUS:85123797377
SN - 2296-634X
VL - 9
JO - Frontiers in Cell and Developmental Biology
JF - Frontiers in Cell and Developmental Biology
M1 - 792185
ER -
