TY - JOUR
T1 - Nanotechnology against COVID-19
T2 - Immunization, diagnostic and therapeutic studies
AU - Hasanzadeh, Akbar
AU - Alamdaran, Masoomeh
AU - Ahmadi, Sepideh
AU - Nourizadeh, Helena
AU - Bagherzadeh, Mohammad Aref
AU - Mofazzal Jahromi, Mirza Ali
AU - Simon, Perikles
AU - Karimi, Mahdi
AU - Hamblin, Michael R.
N1 - Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2021/8/10
Y1 - 2021/8/10
N2 - The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early 2020 soon led to the global pandemic of Coronavirus Disease 2019 (COVID-19). Since then, the clinical and scientific communities have been closely collaborating to develop effective strategies for controlling the ongoing pandemic. The game-changing fields of recent years, nanotechnology and nanomedicine have the potential to not only design new approaches, but also to improve existing methods for the fight against COVID-19. Nanomaterials can be used in the development of highly efficient, reusable personal protective equipment, and antiviral nano-coatings in public settings could prevent the spread of SARS-CoV-2. Smart nanocarriers have accelerated the design of several therapeutic, prophylactic, or immune-mediated approaches against COVID-19. Some nanovaccines have even entered Phase IΙ/IIΙ clinical trials. Several rapid and cost-effective COVID-19 diagnostic techniques have also been devised based on nanobiosensors, lab-on-a-chip systems, or nanopore technology. Here, we provide an overview of the emerging role of nanotechnology in the prevention, diagnosis, and treatment of COVID-19.
AB - The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in early 2020 soon led to the global pandemic of Coronavirus Disease 2019 (COVID-19). Since then, the clinical and scientific communities have been closely collaborating to develop effective strategies for controlling the ongoing pandemic. The game-changing fields of recent years, nanotechnology and nanomedicine have the potential to not only design new approaches, but also to improve existing methods for the fight against COVID-19. Nanomaterials can be used in the development of highly efficient, reusable personal protective equipment, and antiviral nano-coatings in public settings could prevent the spread of SARS-CoV-2. Smart nanocarriers have accelerated the design of several therapeutic, prophylactic, or immune-mediated approaches against COVID-19. Some nanovaccines have even entered Phase IΙ/IIΙ clinical trials. Several rapid and cost-effective COVID-19 diagnostic techniques have also been devised based on nanobiosensors, lab-on-a-chip systems, or nanopore technology. Here, we provide an overview of the emerging role of nanotechnology in the prevention, diagnosis, and treatment of COVID-19.
KW - COVID-19
KW - Diagnosis
KW - Nanotechnology
KW - Nanovaccine
KW - SARS-CoV-2
UR - http://www.scopus.com/inward/record.url?scp=85114385585&partnerID=8YFLogxK
U2 - 10.1016/j.jconrel.2021.06.036
DO - 10.1016/j.jconrel.2021.06.036
M3 - Review article
C2 - 34175366
AN - SCOPUS:85114385585
SN - 0168-3659
VL - 336
SP - 354
EP - 374
JO - Journal of Controlled Release
JF - Journal of Controlled Release
ER -
