Nanomodified Polymers for Bone Regeneration and as Dental Implant

  • Mereena Luke
  • , Tomy Muringayil Joseph
  • , Józef T. Haponiuk
  • , Sabu Thomas

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

The main emphasis on the development of tissue engineering involves the development of functional alternatives for damaged organs or tissues. Scaffolds facilitate cell proliferation while also improving their specific functions. Scaffolds are 3D structures capable of imitating the tissue extracellular matrix’s mechanical and bioactive activities, providing a suitable environment for cellular bonding, proliferation, and distinction. Therefore, in tissue engineering, scaffolds are also assigned to promote defective tissue regeneration, a very essential feature of bone tissue regeneration. Due to their unique versatility, polymers are extensively used in tissue engineering. Polymers are excellent candidates for bone scaffolding; however, they can only achieve the mechanical activity equivalent to that of bones by integrating nanomodification by nanoreinforcement, such as using fibers or uniformly dispersed ceramic or metallic nanoparticles in the matrix. Nanomodification improves the structural and mechanical performance of composites in the biomedical field, especially those used in tissue engineering, bone regeneration, and modern dentistry implants. Therefore, this chapter addresses recent leading studies on nanocomposites in the medical field, especially in tissue engineering and bone regeneration, and explores their competitive advantages and trends.

Original languageEnglish
Title of host publicationNanoengineered Materials for Medical and Healthcare Applications
Publisherwiley
Pages199-225
Number of pages27
ISBN (Electronic)9781119792192
ISBN (Print)9781119791645
DOIs
Publication statusPublished - 1 Jan 2025
Externally publishedYes

Keywords

  • Polymer nanocomposite
  • bone regeneration
  • polymer fiber composites
  • scaffolds
  • tissue engineering

ASJC Scopus subject areas

  • General Engineering
  • General Materials Science

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