Nanoenzyme-Based Electrodes in Biomolecular Screening and Analysis

Ephraim Felix Marondedze, Lukman O. Olasunkanmi, Atheesha Singh, Penny Poomani Govender

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Nanobioelectrochemistry is a multidiscipline branch of science encompassing nanomaterials, biotechnology, and electrochemistry. In principle, nanomaterials with enzyme-like properties, simply referred to as nanozymes, are used in place of natural and traditional artificial enzymes due to their resilience under a wide range of stringent conditions. Additional advantages of nanozymes include extended storage times, cost-effectiveness, and enhanced catalytic properties. Mechanisms of action make use of redox activities to generate a signal that can be used to provide insight on various analytic procedures. Some areas of major application include but are not limited to disease detection and control, in addition to food safety. Herein, we focus on current trends in the use of nanozymes in bioelectrochemistry. Precisely, we highlight how electrodes in nano-bioelectrochemistry may be fabricated for optimum performance. Furthermore, we focus on biosensing techniques, food monitoring, cancer diagnosis, cancer therapy, bacteria detection, and Covid-19 detection as part of current trends in nanozymes in nano-electrochemistry.

Original languageEnglish
Title of host publicationHandbook of Nanobioelectrochemistry
Subtitle of host publicationApplication in Devices and Biomolecular Sensing
Number of pages15
ISBN (Electronic)9789811994371
ISBN (Print)9789811994364
Publication statusPublished - 1 Jan 2023


  • Bioelectrochemistry
  • Hydrolase
  • Nanozymes
  • Oxidoreductase
  • Sensing

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology
  • General Engineering
  • General Materials Science


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