Mushroom-Derived Products as an Alternative Antimalarial Therapeutics: A Review

Senzosenkosi S. Mkhize, Kgothatso E. Machaba, Mthokozisi B.C. Simelane, Ofentse J. Pooe

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)

Abstract

Edible and medicinal mushrooms have been highlighted to contain potent antiparasitic activity, due to their vast phytochemical content. Mushroom can be defined as a macro-fungus with a fruiting body that can be either above or below the ground which can be seen and picked by hands. A number of researchers have documented potent antimalarial effects of crude extracts and isolated compounds derived from medicinal and edible mushrooms. The continued discovery of drug-resistant malaria-causing parasites has necessitated the requirement for novel antimalarial drugs. However, literature on mushrooms as potential antimalarials has not been fully provided; hence, this chapter focuses majorly on the antiparasitic effects of mushroom-derived products and their potential antimalarial capabilities and the possible mechanism of action.

Original languageEnglish
Title of host publicationDrug Development for Malaria
Subtitle of host publicationNovel Approaches for Prevention and Treatment
Publisherwiley
Pages235-249
Number of pages15
ISBN (Electronic)9783527830589
ISBN (Print)9783527348602
DOIs
Publication statusPublished - 1 Jan 2022

ASJC Scopus subject areas

  • General Medicine
  • General Pharmacology, Toxicology and Pharmaceutics

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