Multi-class protein sequence classification using fuzzy ARTMAP

Shakir Mohamed, David Rubin, Tshilidzi Marwala

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

25 Citations (Scopus)

Abstract

The classification of protein sequences into families is an important tool in the annotation of structural and functional properties to newly discovered proteins. We present a classification system using pattern recognition techniques to create a numerical vector representation of a protein sequence and then classify the sequence into a number of given families. We introduce the use of fuzzy ARTMAP classifiers and show that coupled with the genetic algorithm based feature subset selection, the system is able to classify protein sequences with an accuracy of 93 %. This accuracy is compared with numerous other classification tools and demonstrates that the fuzzy ARTMAP is suitable due to its high accuracy, quick training times and ability for incremental learning.

Original languageEnglish
Title of host publication2006 IEEE International Conference on Systems, Man and Cybernetics
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1676-1681
Number of pages6
ISBN (Print)1424401003, 9781424401000
DOIs
Publication statusPublished - 2006
Externally publishedYes
Event2006 IEEE International Conference on Systems, Man and Cybernetics - Taipei, Taiwan, Province of China
Duration: 8 Oct 200611 Oct 2006

Publication series

NameConference Proceedings - IEEE International Conference on Systems, Man and Cybernetics
Volume2
ISSN (Print)1062-922X

Conference

Conference2006 IEEE International Conference on Systems, Man and Cybernetics
Country/TerritoryTaiwan, Province of China
CityTaipei
Period8/10/0611/10/06

ASJC Scopus subject areas

  • General Engineering

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