Modelling Drug Abuse Epidemics in the Presence of Limited Rehabilitation Capacity

J. Mushanyu, F. Nyabadza, G. Muchatibaya, A. G.R. Stewart

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

The abuse of drugs is now an epidemic globally whose control has been mainly through rehabilitation. The demand for drug abuse rehabilitation has not been matched with the available capacity resulting in limited placement of addicts into rehabilitation. In this paper, we model limited rehabilitation through the Hill function incorporated into a system of nonlinear ordinary differential equations. Not every member of the community is equally likely to embark on drug use, risk structure is included to help differentiate those more likely (high risk) to abuse drugs and those less likely (low risk) to abuse drugs. It is shown that the model has multiple equilibria, and using the centre manifold theory, the model exhibits the phenomenon of backward bifurcation whose implications to rehabilitation are discussed. Sensitivity analysis and numerical simulations are performed. The results show that saturation in rehabilitation will in the long run lead to the escalation of drug abuse. This means that limited access to rehabilitation has negative implications in the fight against drug abuse where rehabilitation is the main form of control. This suggests that increased access to rehabilitation is likely to lower the drug abuse epidemic.

Original languageEnglish
Pages (from-to)2364-2389
Number of pages26
JournalBulletin of Mathematical Biology
Volume78
Issue number12
DOIs
Publication statusPublished - 1 Dec 2016
Externally publishedYes

Keywords

  • Drug abuse
  • Hill function
  • Rehabilitation capacity
  • Reproduction number

ASJC Scopus subject areas

  • General Neuroscience
  • Immunology
  • General Mathematics
  • General Biochemistry,Genetics and Molecular Biology
  • General Environmental Science
  • Pharmacology
  • General Agricultural and Biological Sciences
  • Computational Theory and Mathematics

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