@inbook{c4698fd5a3954f81867aa93041e1d9db,
title = "MicroRNAs in Cancer",
abstract = "The dysr{\'e}gulation of microRNAs in cancer was first reported in 2002, when a cluster of two microRNAs (miR16 and miR-15) was detected at chromosome 13q14.3, which had been proposed as one of the commonly eliminated genetic regions in chronic lymphocytic leukemia (CLL) patients [1]. The deletion of this miRNA cluster acts (at least partly) by increasing the expression level of the specific target of miR-15/16, which is the anti-apoptotic protein B cell lymphoma 2 (BCL2). It has been found that micro-RNAs can contribute to each cancer hallmark described by Hanahan and Weinberg [2], as well affecting the clinical progression of many cancers at different stages.",
author = "Hamed Mirzaei and Neda Rahimian and Mirzaei, {Hamid Reza} and Nahand, {Javid Sadri} and Hamblin, {Michael R.}",
note = "Publisher Copyright: {\textcopyright} 2022, Springer Nature Switzerland AG.",
year = "2022",
doi = "10.1007/978-3-031-79177-2_2",
language = "English",
series = "Synthesis Lectures on Biomedical Engineering",
publisher = "Springer Nature",
pages = "11--40",
booktitle = "Synthesis Lectures on Biomedical Engineering",
address = "United States",
}
