Microfluidic devices with gold thin film channels for chemical and biomedical applications: a review

Mahtab Ghasemi Toudeshkchoui, Navid Rabiee, Mohammad Rabiee, Mojtaba Bagherzadeh, Mohammadreza Tahriri, Lobat Tayebi, Michael R. Hamblin

Research output: Contribution to journalArticlepeer-review

23 Citations (Scopus)

Abstract

Microfluidic systems (MFS) provide a range of advantages in biomedical applications, including improved controllability of material characteristics and lower consumption of reagents, energy, time and money. Fabrication of MFS employs various materials, such as glass, silicon, ceramics, paper, and metals such as gold, copper, aluminum, chromium and titanium. In this review, gold thin film microfluidic channels (GTFMFC) are discussed with reference to fabrication methods and their diverse use in chemical and biomedical applications. The advantages of gold thin films (GTF) include flexibility, ease of manufacture, adhesion to polymer surfaces, chemical stability, good electrical conductivity, surface plasmon resonance effects, ability to be chemically functionalized, etc. Various electroactuators and electroanalytical devices can incorporate GTF. GTF-based MFS have been used in environmental monitoring, assays of biomarkers, immunoassays, cell culture studies and pathogen identification.

Original languageEnglish
Article number93
JournalBiomedical Microdevices
Volume21
Issue number4
DOIs
Publication statusPublished - 1 Dec 2019
Externally publishedYes

Keywords

  • Biomedical applications
  • Electrochemical sensors
  • Gold thin film channels
  • Microfluidic systems
  • Surface plasmonic resonance

ASJC Scopus subject areas

  • Biomedical Engineering
  • Molecular Biology

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