MgO-ZnO/carbon nanofiber nanocomposite as an adsorbent for ultrasound-assisted dispersive solid-phase microextraction of carbamazepine from wastewater prior to high-performance liquid chromatographic detection

Malesela William Lekota, K. Mogolodi Dimpe, Philiswa Nosizo Nomngongo

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

A simple, rapid, and efficient ultrasound-assisted dispersive solid-phase microextraction (UA-DSPME) method was developed for the preconcentration of carbamazepine (CBZ) in wastewater prior to high-performance liquid chromatography coupled with diode array (HPLC-DAD) determination. The carbon nanofibers coated with magnesium oxide-zinc oxide (MgO-ZnO@CNFs) nanocomposite was used as an efficient adsorbent in magnetic dispersive solid-phase microextraction method. The structural and morphological properties of the nanocomposite were characterized by scanning electron microscopy and energy dispersive spectroscopy, transmission electron microscopy, X-ray diffractometer, and Fourier transform infrared spectroscopy. The surface area was investigated using Brunauer–Emmett–Teller. Several factors (such as pH, mass of adsorbent, extraction time, and eluent volume) that affect extraction and preconcentration of CBZ were also assessed and optimized using response surface methodology based on central composite design. Under optimal conditions, the limits of detection (LOD) and quantification were 0.08 μg L−1 and 0.29 μg L−1, respectively. The calibration curve constructed after preconcentration of seven successive standards was linear in the concentration range of 0.3–800 μg L−1 with the correlation coefficient of 0.9922. The intra-day and inter-day precisions expressed in terms of relative standard deviation were 1.4% and 4.2%. A preconcentration factor of 490 was achieved, and the method was applied for the analysis of spiked wastewater. Satisfactory recoveries ranging from 97.8 to 102% were obtained.

Original languageEnglish
Article number25
JournalJournal of Analytical Science and Technology
Volume10
Issue number1
DOIs
Publication statusPublished - 1 Dec 2019

Keywords

  • Carbamazepine
  • Desirability function
  • Dispersive solid-phase microextraction
  • MgO-ZnO@CNFs nanocomposite

ASJC Scopus subject areas

  • General Biochemistry,Genetics and Molecular Biology
  • General Chemistry
  • General Environmental Science
  • General Materials Science
  • General Physics and Astronomy

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