TY - JOUR
T1 - Magnetic beta cyclodextrin molecularly imprinted polymer for selective extraction of perfluorooctanoic acid from water
AU - Malatji, Nompumelelo
AU - Mpupa, Anele
AU - Mizaikoff, Boris
AU - Nomngongo, Philiswa Nosizo
N1 - Publisher Copyright:
© 2025 The Author(s)
PY - 2025/8/15
Y1 - 2025/8/15
N2 - The association of PFOA with low concentrations and complex water matrices has made its direct quantification using sensitive analytical methods such as UHPLC-ESI-MS/MS challenging. This study used a magnetic beta-cyclodextrin-based molecularly imprinted polymer (TWAC-Fe3O4@β-CD-MIP) prepared via surface imprinting on magnetic tea waste activated carbon (TWAC-Fe3O4). Under optimal conditions, the method exhibited a linear range (17–5000 ng/L, R2 = 0.9990) in real water, with LOD and LOQ of 8.6 ng/L and 29 ng/L, respectively. Precision was high, with intraday and interday %RSD of 2.1% and 3.7%. The adsorbent was reusable for three cycles while maintaining over 60% recovery. Spike recoveries in water samples ranged from 102 to 106% with %RSD <5%, confirming the method's accuracy. The imprinting factor was 5.57, and adsorption followed the Sips isotherm model. This study explored MIPs for PFOA determination in water.
AB - The association of PFOA with low concentrations and complex water matrices has made its direct quantification using sensitive analytical methods such as UHPLC-ESI-MS/MS challenging. This study used a magnetic beta-cyclodextrin-based molecularly imprinted polymer (TWAC-Fe3O4@β-CD-MIP) prepared via surface imprinting on magnetic tea waste activated carbon (TWAC-Fe3O4). Under optimal conditions, the method exhibited a linear range (17–5000 ng/L, R2 = 0.9990) in real water, with LOD and LOQ of 8.6 ng/L and 29 ng/L, respectively. Precision was high, with intraday and interday %RSD of 2.1% and 3.7%. The adsorbent was reusable for three cycles while maintaining over 60% recovery. Spike recoveries in water samples ranged from 102 to 106% with %RSD <5%, confirming the method's accuracy. The imprinting factor was 5.57, and adsorption followed the Sips isotherm model. This study explored MIPs for PFOA determination in water.
KW - Chemistry
KW - Environmental technology
KW - Materials science
KW - Molecular imprinted technique
KW - Nanomaterials
UR - https://www.scopus.com/pages/publications/105012414822
U2 - 10.1016/j.isci.2025.113205
DO - 10.1016/j.isci.2025.113205
M3 - Article
AN - SCOPUS:105012414822
SN - 2589-0042
VL - 28
JO - iScience
JF - iScience
IS - 8
M1 - 113205
ER -