Low intensity laser irradiation stimulates healing in stressed models

N. Houreld; P. R. Sekhejane; H. Abrahamse

Low intensity laser irradiation stimulates healing in stressed models

N. Houreld
, P. R. Sekhejane
, H. Abrahamse

Laser Research Centre

University of Johannesburg

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Citations (Scopus)

Abstract

Wound healing in diabetic patients remains a complicated problem and there is a compelling need for the development of new, safe, reliable therapies. This study looked at the effect of low intensity laser irradiation (LILI) on diabetic wound healing in vitro. Induced diabetic wounded and hypoxic human fibroblast cells were irradiated at 636 nm with 5 J/cm². Post-irradiation stressed cells showed increased viability and proliferation and a decrease in apoptosis and pro-inflammatory cytokines (IL-1β and TNF-α). The models used are sufficient to produce measurable effects as compared to normal cells. LILI positively effects wound healing in stressed models, normalises cellular function, and directs cells into cell survival pathways.

Original language	English
Title of host publication	Updates from 8th International Congress of the World Association of Laser Therapy, WALT 2010
Publisher	MEDIMOND s.r.l.
Pages	23-26
Number of pages	4
Edition	1
ISBN (Print)	9788875875978
Publication status	Published - 2010
Event	8th International Congress of the World Association of Laser Therapy, WALT 2010 - Bergen, Norway Duration: 25 Sept 2010 → 28 Sept 2010

Publication series

Name	Proceedings of the 8th International Congress of the World Association of Laser Therapy, WALT 2010
Number	1
Volume	1

Conference

Conference	8th International Congress of the World Association of Laser Therapy, WALT 2010
Country/Territory	Norway
City	Bergen
Period	25/09/10 → 28/09/10

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

General Medicine

Cite this

Houreld, N., Sekhejane, P. R., & Abrahamse, H. (2010). Low intensity laser irradiation stimulates healing in stressed models. In Updates from 8th International Congress of the World Association of Laser Therapy, WALT 2010 (1 ed., pp. 23-26). (Proceedings of the 8th International Congress of the World Association of Laser Therapy, WALT 2010; Vol. 1, No. 1). MEDIMOND s.r.l..

@inproceedings{1c0a041147374269a60aee410ed087c5,

title = "Low intensity laser irradiation stimulates healing in stressed models",

abstract = "Wound healing in diabetic patients remains a complicated problem and there is a compelling need for the development of new, safe, reliable therapies. This study looked at the effect of low intensity laser irradiation (LILI) on diabetic wound healing in vitro. Induced diabetic wounded and hypoxic human fibroblast cells were irradiated at 636 nm with 5 J/cm2. Post-irradiation stressed cells showed increased viability and proliferation and a decrease in apoptosis and pro-inflammatory cytokines (IL-1β and TNF-α). The models used are sufficient to produce measurable effects as compared to normal cells. LILI positively effects wound healing in stressed models, normalises cellular function, and directs cells into cell survival pathways.",

author = "N. Houreld and Sekhejane, \{P. R.\} and H. Abrahamse",

year = "2010",

language = "English",

isbn = "9788875875978",

series = "Proceedings of the 8th International Congress of the World Association of Laser Therapy, WALT 2010",

publisher = "MEDIMOND s.r.l.",

number = "1",

pages = "23--26",

booktitle = "Updates from 8th International Congress of the World Association of Laser Therapy, WALT 2010",

edition = "1",

note = "8th International Congress of the World Association of Laser Therapy, WALT 2010 ; Conference date: 25-09-2010 Through 28-09-2010",

}

Houreld, N, Sekhejane, PR & Abrahamse, H 2010, Low intensity laser irradiation stimulates healing in stressed models. in Updates from 8th International Congress of the World Association of Laser Therapy, WALT 2010. 1 edn, Proceedings of the 8th International Congress of the World Association of Laser Therapy, WALT 2010, no. 1, vol. 1, MEDIMOND s.r.l., pp. 23-26, 8th International Congress of the World Association of Laser Therapy, WALT 2010, Bergen, Norway, 25/09/10.

Low intensity laser irradiation stimulates healing in stressed models. / Houreld, N.; Sekhejane, P. R.; Abrahamse, H.
Updates from 8th International Congress of the World Association of Laser Therapy, WALT 2010. 1. ed. MEDIMOND s.r.l., 2010. p. 23-26 (Proceedings of the 8th International Congress of the World Association of Laser Therapy, WALT 2010; Vol. 1, No. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Low intensity laser irradiation stimulates healing in stressed models

AU - Houreld, N.

AU - Sekhejane, P. R.

AU - Abrahamse, H.

PY - 2010

Y1 - 2010

N2 - Wound healing in diabetic patients remains a complicated problem and there is a compelling need for the development of new, safe, reliable therapies. This study looked at the effect of low intensity laser irradiation (LILI) on diabetic wound healing in vitro. Induced diabetic wounded and hypoxic human fibroblast cells were irradiated at 636 nm with 5 J/cm2. Post-irradiation stressed cells showed increased viability and proliferation and a decrease in apoptosis and pro-inflammatory cytokines (IL-1β and TNF-α). The models used are sufficient to produce measurable effects as compared to normal cells. LILI positively effects wound healing in stressed models, normalises cellular function, and directs cells into cell survival pathways.

AB - Wound healing in diabetic patients remains a complicated problem and there is a compelling need for the development of new, safe, reliable therapies. This study looked at the effect of low intensity laser irradiation (LILI) on diabetic wound healing in vitro. Induced diabetic wounded and hypoxic human fibroblast cells were irradiated at 636 nm with 5 J/cm2. Post-irradiation stressed cells showed increased viability and proliferation and a decrease in apoptosis and pro-inflammatory cytokines (IL-1β and TNF-α). The models used are sufficient to produce measurable effects as compared to normal cells. LILI positively effects wound healing in stressed models, normalises cellular function, and directs cells into cell survival pathways.

UR - https://www.scopus.com/pages/publications/84902477337

M3 - Conference contribution

AN - SCOPUS:84902477337

SN - 9788875875978

T3 - Proceedings of the 8th International Congress of the World Association of Laser Therapy, WALT 2010

SP - 23

EP - 26

BT - Updates from 8th International Congress of the World Association of Laser Therapy, WALT 2010

PB - MEDIMOND s.r.l.

T2 - 8th International Congress of the World Association of Laser Therapy, WALT 2010

Y2 - 25 September 2010 through 28 September 2010

ER -

Low intensity laser irradiation stimulates healing in stressed models

Abstract

Publication series

Conference

UN SDGs

ASJC Scopus subject areas

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