Low intensity laser irradiation stimulates healing in stressed models

N. Houreld, P. R. Sekhejane, H. Abrahamse

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

2 Citations (Scopus)

Abstract

Wound healing in diabetic patients remains a complicated problem and there is a compelling need for the development of new, safe, reliable therapies. This study looked at the effect of low intensity laser irradiation (LILI) on diabetic wound healing in vitro. Induced diabetic wounded and hypoxic human fibroblast cells were irradiated at 636 nm with 5 J/cm2. Post-irradiation stressed cells showed increased viability and proliferation and a decrease in apoptosis and pro-inflammatory cytokines (IL-1β and TNF-α). The models used are sufficient to produce measurable effects as compared to normal cells. LILI positively effects wound healing in stressed models, normalises cellular function, and directs cells into cell survival pathways.

Original languageEnglish
Title of host publicationUpdates from 8th International Congress of the World Association of Laser Therapy, WALT 2010
PublisherMEDIMOND s.r.l.
Pages23-26
Number of pages4
Edition1
ISBN (Print)9788875875978
Publication statusPublished - 2010
Event8th International Congress of the World Association of Laser Therapy, WALT 2010 - Bergen, Norway
Duration: 25 Sept 201028 Sept 2010

Publication series

NameProceedings of the 8th International Congress of the World Association of Laser Therapy, WALT 2010
Number1
Volume1

Conference

Conference8th International Congress of the World Association of Laser Therapy, WALT 2010
Country/TerritoryNorway
CityBergen
Period25/09/1028/09/10

ASJC Scopus subject areas

  • General Medicine

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