Laser irradiation in the visible wavelength stimulates wound healing in vitro

N. N. Houreld

Laser irradiation in the visible wavelength stimulates wound healing in vitro

N. N. Houreld

Laser Research Centre

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Low intensity laser irradiation (LILI) has been applied to stimulate healing in a variety of conditions, such as diabetes. This study aimed to determine the biochemical and molecular responses to LILI in the visible red spectrum. Various cell culture models, namely wounded, diabetic wounded and hypoxic/ischemic were used. Models were exposed to visible red laser light (632.8, 636 or 660 nm) at a fluence of 5 J/cm². Post-irradiation, the effect on cells was studied. Laser irradiation was shown to have a positive effect on stressed cells in vitro. There was an increase in migration, cell survival and proliferation, mitochondrial activity, secondary messengers and collagen. A decrease in cytotoxicity, DNA damage and pro-inflammatory cytokines were also seen. LLLT offers an alternative wound healing therapy. At a biochemical level there was a positive effect on cells, with stressed cells being pushed into cell survival pathways.

Original language	English
Title of host publication	Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012
Publisher	MEDIMOND s.r.l.
Pages	41-44
Number of pages	4
ISBN (Print)	9788875876777
Publication status	Published - 2012
Event	9th World Association for Laser Therapy Congress, WALT 2012 - Surfers Paradise, QT Gold Coast, Australia Duration: 28 Sept 2012 → 30 Sept 2012

Publication series

Name	Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012

Conference

Conference	9th World Association for Laser Therapy Congress, WALT 2012
Country/Territory	Australia
City	Surfers Paradise, QT Gold Coast
Period	28/09/12 → 30/09/12

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

ASJC Scopus subject areas

Biomedical Engineering
Dermatology
Surgery

Cite this

@inproceedings{c58b9ca8ced14717bf3da150cfbcd74f,

title = "Laser irradiation in the visible wavelength stimulates wound healing in vitro",

abstract = "Low intensity laser irradiation (LILI) has been applied to stimulate healing in a variety of conditions, such as diabetes. This study aimed to determine the biochemical and molecular responses to LILI in the visible red spectrum. Various cell culture models, namely wounded, diabetic wounded and hypoxic/ischemic were used. Models were exposed to visible red laser light (632.8, 636 or 660 nm) at a fluence of 5 J/cm2. Post-irradiation, the effect on cells was studied. Laser irradiation was shown to have a positive effect on stressed cells in vitro. There was an increase in migration, cell survival and proliferation, mitochondrial activity, secondary messengers and collagen. A decrease in cytotoxicity, DNA damage and pro-inflammatory cytokines were also seen. LLLT offers an alternative wound healing therapy. At a biochemical level there was a positive effect on cells, with stressed cells being pushed into cell survival pathways.",

author = "Houreld, \{N. N.\}",

year = "2012",

language = "English",

isbn = "9788875876777",

series = "Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012",

publisher = "MEDIMOND s.r.l.",

pages = "41--44",

booktitle = "Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012",

note = "9th World Association for Laser Therapy Congress, WALT 2012 ; Conference date: 28-09-2012 Through 30-09-2012",

}

Houreld, NN 2012, Laser irradiation in the visible wavelength stimulates wound healing in vitro. in Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012. Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012, MEDIMOND s.r.l., pp. 41-44, 9th World Association for Laser Therapy Congress, WALT 2012, Surfers Paradise, QT Gold Coast, Australia, 28/09/12.

Laser irradiation in the visible wavelength stimulates wound healing in vitro. / Houreld, N. N.
Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012. MEDIMOND s.r.l., 2012. p. 41-44 (Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Laser irradiation in the visible wavelength stimulates wound healing in vitro

AU - Houreld, N. N.

PY - 2012

Y1 - 2012

N2 - Low intensity laser irradiation (LILI) has been applied to stimulate healing in a variety of conditions, such as diabetes. This study aimed to determine the biochemical and molecular responses to LILI in the visible red spectrum. Various cell culture models, namely wounded, diabetic wounded and hypoxic/ischemic were used. Models were exposed to visible red laser light (632.8, 636 or 660 nm) at a fluence of 5 J/cm2. Post-irradiation, the effect on cells was studied. Laser irradiation was shown to have a positive effect on stressed cells in vitro. There was an increase in migration, cell survival and proliferation, mitochondrial activity, secondary messengers and collagen. A decrease in cytotoxicity, DNA damage and pro-inflammatory cytokines were also seen. LLLT offers an alternative wound healing therapy. At a biochemical level there was a positive effect on cells, with stressed cells being pushed into cell survival pathways.

AB - Low intensity laser irradiation (LILI) has been applied to stimulate healing in a variety of conditions, such as diabetes. This study aimed to determine the biochemical and molecular responses to LILI in the visible red spectrum. Various cell culture models, namely wounded, diabetic wounded and hypoxic/ischemic were used. Models were exposed to visible red laser light (632.8, 636 or 660 nm) at a fluence of 5 J/cm2. Post-irradiation, the effect on cells was studied. Laser irradiation was shown to have a positive effect on stressed cells in vitro. There was an increase in migration, cell survival and proliferation, mitochondrial activity, secondary messengers and collagen. A decrease in cytotoxicity, DNA damage and pro-inflammatory cytokines were also seen. LLLT offers an alternative wound healing therapy. At a biochemical level there was a positive effect on cells, with stressed cells being pushed into cell survival pathways.

UR - https://www.scopus.com/pages/publications/84902449048

M3 - Conference contribution

AN - SCOPUS:84902449048

SN - 9788875876777

T3 - Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012

SP - 41

EP - 44

BT - Proceedings of the 9th World Association for Laser Therapy Congress, WALT 2012

PB - MEDIMOND s.r.l.

T2 - 9th World Association for Laser Therapy Congress, WALT 2012

Y2 - 28 September 2012 through 30 September 2012

ER -

Laser irradiation in the visible wavelength stimulates wound healing in vitro

Abstract

Publication series

Conference

UN SDGs

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this