Introduction to polymeric in situ forming hydrogels for ophthalmic drug delivery

Jonathan Tersur Orasugh, Dipankar Chattopadhayay, Suprakas Sinha Ray, Anjan Adhikari

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Ocular drug delivery is a complex and challenging field that requires innovative approaches to improve drug efficacy and patient compliance. In this introductory chapter, we provide an overview of the use of polymeric in situ forming hydrogels as a promising strategy for enhancing ophthalmic drug delivery. This chapter begins by highlighting the importance of effective drug delivery to the eye and the unique anatomical and physiological barriers that make this task particularly challenging. It underscores the critical need for controlled and sustained drug release within the ocular environment. As we conclude this introductory chapter, we also touch upon recent advancements and emerging trends in the field, such as stimuli-responsive hydrogels and nanotechnology-based approaches, which hold great promise for achieving precise control over drug release and optimizing therapeutic outcomes in ophthalmology. In summary, this chapter serves as a foundational overview, laying the groundwork for the subsequent chapters in this book dedicated to exploring the intricacies, challenges, and innovations in the realm of polymeric in situ forming hydrogels for ophthalmic drug delivery. It is intended to be a valuable resource for researchers, clinicians, and pharmaceutical scientists seeking to navigate and contribute to this evolving field.

Original languageEnglish
Title of host publicationStimuli-Responsive Hydrogels for Ophthalmic Drug Delivery
PublisherElsevier
Pages29-56
Number of pages28
ISBN (Electronic)9780323991568
ISBN (Print)9780323993593
DOIs
Publication statusPublished - 1 Jan 2024

Keywords

  • In situ forming hydrogels
  • Ocular diseases
  • Ophthalmic drug delivery
  • Polymeric hydrogels

ASJC Scopus subject areas

  • General Engineering
  • General Materials Science

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