Innate lymphoid cell subsets and their cytokines in autoimmune diseases

Asma Maleki, Jamal Motallebzadeh Khanmiri, Mohammad Khani Eshrat Abadi, Faezeh Soveyzi, Bobak Moazzami, Michael R. Hamblin, Nima Rezaei

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


Both the innate and adaptive arms of the immune system are involved in the development of autoimmune diseases. The main mechanism of disease is due to adaptive immune cells that are active against self-antigens. These cells can cause major damage to body tissues. Innate lymphoid cells (ILCs) are an important type of innate immune cell, whose role has been highlighted in recent years. ILCs are responsible for some of the inflammation in the pathogenesis of autoimmune diseases. In this review, we discuss the role of ILCs in the immune response, as well as their involvement in various autoimmune diseases.

Original languageEnglish
Pages (from-to)118-128
Number of pages11
JournalEuropean Cytokine Network
Issue number4
Publication statusPublished - Dec 2020


  • autoimmunity
  • cytokines
  • innate lymphoid cells
  • mucosal immune response

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Clinical Biochemistry


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