Innate lymphoid cell subsets and their cytokines in autoimmune diseases

Asma Maleki; Jamal Motallebzadeh Khanmiri; Mohammad Khani Eshrat Abadi; Faezeh Soveyzi; Bobak Moazzami; Michael R. Hamblin; Nima Rezaei

doi:10.1684/ecn.2020.0460

Innate lymphoid cell subsets and their cytokines in autoimmune diseases

Asma Maleki, Jamal Motallebzadeh Khanmiri, Mohammad Khani Eshrat Abadi, Faezeh Soveyzi, Bobak Moazzami, Michael R. Hamblin, Nima Rezaei

Laser Research Centre

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Abstract

Both the innate and adaptive arms of the immune system are involved in the development of autoimmune diseases. The main mechanism of disease is due to adaptive immune cells that are active against self-antigens. These cells can cause major damage to body tissues. Innate lymphoid cells (ILCs) are an important type of innate immune cell, whose role has been highlighted in recent years. ILCs are responsible for some of the inflammation in the pathogenesis of autoimmune diseases. In this review, we discuss the role of ILCs in the immune response, as well as their involvement in various autoimmune diseases.

Original language	English
Pages (from-to)	118-128
Number of pages	11
Journal	European Cytokine Network
Volume	31
Issue number	4
DOIs	https://doi.org/10.1684/ecn.2020.0460
Publication status	Published - Dec 2020

Keywords

autoimmunity
cytokines
innate lymphoid cells
mucosal immune response

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Clinical Biochemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1684/ecn.2020.0460

Cite this

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title = "Innate lymphoid cell subsets and their cytokines in autoimmune diseases",

abstract = "Both the innate and adaptive arms of the immune system are involved in the development of autoimmune diseases. The main mechanism of disease is due to adaptive immune cells that are active against self-antigens. These cells can cause major damage to body tissues. Innate lymphoid cells (ILCs) are an important type of innate immune cell, whose role has been highlighted in recent years. ILCs are responsible for some of the inflammation in the pathogenesis of autoimmune diseases. In this review, we discuss the role of ILCs in the immune response, as well as their involvement in various autoimmune diseases.",

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AU - Maleki, Asma

AU - Khanmiri, Jamal Motallebzadeh

AU - Eshrat Abadi, Mohammad Khani

AU - Soveyzi, Faezeh

AU - Moazzami, Bobak

AU - Hamblin, Michael R.

AU - Rezaei, Nima

PY - 2020/12

Y1 - 2020/12

N2 - Both the innate and adaptive arms of the immune system are involved in the development of autoimmune diseases. The main mechanism of disease is due to adaptive immune cells that are active against self-antigens. These cells can cause major damage to body tissues. Innate lymphoid cells (ILCs) are an important type of innate immune cell, whose role has been highlighted in recent years. ILCs are responsible for some of the inflammation in the pathogenesis of autoimmune diseases. In this review, we discuss the role of ILCs in the immune response, as well as their involvement in various autoimmune diseases.

AB - Both the innate and adaptive arms of the immune system are involved in the development of autoimmune diseases. The main mechanism of disease is due to adaptive immune cells that are active against self-antigens. These cells can cause major damage to body tissues. Innate lymphoid cells (ILCs) are an important type of innate immune cell, whose role has been highlighted in recent years. ILCs are responsible for some of the inflammation in the pathogenesis of autoimmune diseases. In this review, we discuss the role of ILCs in the immune response, as well as their involvement in various autoimmune diseases.

KW - autoimmunity

KW - cytokines

KW - innate lymphoid cells

KW - mucosal immune response

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ER -

Innate lymphoid cell subsets and their cytokines in autoimmune diseases

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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