Imaging in photodynamic therapy

This chapter will focus on the clinical applications of fluorescence imaging of photosensitizers in skin, in particular, the imaging of photosensitizers in connection to photodynamic therapy (PDT). It is possible to divide this topic into three main objectives: 1) fluorescence imaging with the aim to provide skin cancer diagnostics, 2) fluorescence monitoring to predict clinical outcome of PDT, and 3) the implementation of fluorescence techniques in the discovery of new photosensitizers to improve clinical PDT. Since these topics are closely connected, and it is impossible to introduce one without touching upon another, this chapter will cover all the aforementioned topics by presenting the clinical applications of imaging photosensitizers in skin, and the available techniques for fluorescence imaging.