Functionalization of graphene oxide and its applications in tissue engineering and regenerative medicine

The unique physical and chemical characteristics of graphene oxide (GO) have recently attracted great attention, which highlighted its potential as a promising material for electronic, industrial, biomedical and others potential applications. GO has several functional groups of oxygen, which makes it easier to make GO dispersed in aqueous solution insulating in nature. The functionalization and surface modification of GO is one of the strategies that recently attracted much attention for various electrochemical and biological applications. In general overview, for the functionalization of GO surface, some methods have been proposed that make it possible for the GO-based materials and electrodes for various applications. This comprehensive review focuses on the promising characteristics and recent advances in the functionalization of GO, benefits and limitations, for regenerative medicine and tissue engineering applications.