Food and Environmental Samples Handling and Preparation for Mass Spectrometry

Philiswa Nosizo Nomngongo, Azile Nqombolo, Anele Mpupa

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


In current food safety and environmental monitoring, mass spectrometry methodologies are widely used for identification and quantification of various substances. However, studies have shown that various compounds in food and environment samples are found at ultra-trace concentration levels and the complexity of the sample matrix might limit the performance of selective and sensitive analytical method. Therefore, selection of a proper sampling strategy and sample preparation methods plays a critical role in achieving accurate and reliable results. Thus, this chapter is mainly focused on the recent trends in sample handling and preparation of food and environmental samples prior to MS analysis. Methodologies regarding mass spectrometry coupled with chromatographic separation have been reviewed to highlight the improvement in the analytical determinations of various compounds in food and environmental samples.

Original languageEnglish
Title of host publicationHandbook of Environmental Chemistry
PublisherSpringer Science and Business Media Deutschland GmbH
Number of pages27
Publication statusPublished - 2023

Publication series

NameHandbook of Environmental Chemistry
ISSN (Print)1867-979X


  • Environmental monitoring
  • Food samples
  • Sample handling
  • Solid phase extraction
  • Stir-bar-sorptive extraction

ASJC Scopus subject areas

  • Global and Planetary Change
  • Environmental Chemistry
  • Water Science and Technology
  • Waste Management and Disposal
  • Pollution


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