@inproceedings{3503aa039f2b4a28adbd0a126bf1069f,
title = "Facile green synthesis and characterization of water soluble superparamagnetic iron oxide-gold porphyrin conjugate for improved photodynamic therapy",
abstract = "Porphyrin has been proven to be an efficient photosensitizer for photodynamic therapy (PDT). However, the problem of undesired localization in non-tumour environments has lowered its therapeutic efficacy. To make porphyrin tumour specific, we have successfully conjugated a meso-substituted symmetric 4-hydroxyphenyl porphyrin (THPP) to superparamagnetic iron oxide nanoparticles-gold core-shell nanostructure (SPIONs-Au). The magnetic porphyrin conjugate (MPC) was characterized using UV-Visible spectrophotometry (UV-Vis), Photoluminescence spectroscopy (PL) and Fourier Transform infrared spectroscopy (FT-IR). The as-synthesized MPC exhibited strong attraction towards external magnetic field and high singlet oxygen quantum yield sufficient for the eradication of cancer cells in vitro.",
keywords = "Breast cancer, Gold, Magnetic targeting, PDT, Porphyrin, SPIONs",
author = "Fakayode, {Olayemi J.} and Songca, {Sandile P.} and Oluwafemi, {Oluwatobi S.}",
note = "Publisher Copyright: {\textcopyright} The Minerals, Metals & Materials Society 2017.; 146th Annual Meeting and Exhibition Supplemental, TMS 2017 ; Conference date: 26-02-2017 Through 02-03-2017",
year = "2017",
doi = "10.1007/978-3-319-51493-2_3",
language = "English",
isbn = "9783319514925",
series = "Minerals, Metals and Materials Series",
publisher = "Springer International Publishing",
pages = "23--27",
booktitle = "TMS 2017 146th Annual Meeting",
}
