Facile diastereoselective synthesis of carbohydrate-based thiochromans

Henok H. Kinfe, Paseka T. Moshapo, Felix L. Makolo, Alfred Muller

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

An efficient and novel diastereoselective thiochroman synthesis using the carbohydrate chiral pool via intramolecular Friedel-Crafts alkylation is presented. The scope and limitations of the method are investigated.

Original languageEnglish
Pages (from-to)139-157
Number of pages19
JournalJournal of Carbohydrate Chemistry
Volume32
Issue number2
DOIs
Publication statusPublished - 12 Feb 2013

Keywords

  • Carbohydrate
  • Friedel-Crafts Alkylation
  • Thiochroman

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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