Fabrication of silicon quantum dots-methyl viologen nanohybrids: Turn-On-Off-On fluorescence nanoprobe for the detection of d-penicillamine

Kalimuthu Rajendran; Mattath Mohamed Nabeel; Kannaiyan Pandian; Velu Manikandan; Sivarasan Ganesan; Huang Mu Lo; Nagappan Rajendiran; Xinghui Liu; Oluwatobi Samuel Oluwafemi

doi:10.1016/j.microc.2023.109803

Fabrication of silicon quantum dots-methyl viologen nanohybrids: Turn-On-Off-On fluorescence nanoprobe for the detection of d-penicillamine

Kalimuthu Rajendran, Mattath Mohamed Nabeel, Kannaiyan Pandian, Velu Manikandan, Sivarasan Ganesan, Huang Mu Lo, Nagappan Rajendiran, Xinghui Liu, Oluwatobi Samuel Oluwafemi

Chemical Sciences

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

This study provides a straightforward, one-step hydrothermal approach for synthesizing water-soluble silicon quantum dots (SiQDs). The surface of the synthesized SiQDs is modified by the carboxylic acid functional group (A:SiQDs) after succinic anhydride treatment. The modified A:SiQDs, which emitted blue light fluorescence, showed high stability against photobleaching, thermal stability, and good water solubility. The A:SiQDs are conjugated with methyl viologen (MV²⁺) to develop a nanohybrid for specific D-Penicillamine (D-PA) detection with an LOD of 8 nM. The suggested sensor was effectively used to analyze D-PA in commercial pharmaceutical formulations using the conventional addition method, and it produced results with good accuracy and precision that were nearly equal to those measured.

Original language	English
Article number	109803
Journal	Microchemical Journal
Volume	197
DOIs	https://doi.org/10.1016/j.microc.2023.109803
Publication status	Published - Feb 2024

Keywords

D-Penicillamine
Methyl Viologen
Nanohybrids
Silicon Quantum Dots
Turn-On-Off-On sensing

ASJC Scopus subject areas

Analytical Chemistry
Spectroscopy

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10.1016/j.microc.2023.109803

Cite this

Rajendran, K., Mohamed Nabeel, M., Pandian, K., Manikandan, V., Ganesan, S., Lo, H. M., Rajendiran, N., Liu, X., & Samuel Oluwafemi, O. (2024). Fabrication of silicon quantum dots-methyl viologen nanohybrids: Turn-On-Off-On fluorescence nanoprobe for the detection of d-penicillamine. Microchemical Journal, 197, Article 109803. https://doi.org/10.1016/j.microc.2023.109803

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title = "Fabrication of silicon quantum dots-methyl viologen nanohybrids: Turn-On-Off-On fluorescence nanoprobe for the detection of d-penicillamine",

abstract = "This study provides a straightforward, one-step hydrothermal approach for synthesizing water-soluble silicon quantum dots (SiQDs). The surface of the synthesized SiQDs is modified by the carboxylic acid functional group (A:SiQDs) after succinic anhydride treatment. The modified A:SiQDs, which emitted blue light fluorescence, showed high stability against photobleaching, thermal stability, and good water solubility. The A:SiQDs are conjugated with methyl viologen (MV2+) to develop a nanohybrid for specific D-Penicillamine (D-PA) detection with an LOD of 8 nM. The suggested sensor was effectively used to analyze D-PA in commercial pharmaceutical formulations using the conventional addition method, and it produced results with good accuracy and precision that were nearly equal to those measured.",

keywords = "D-Penicillamine, Methyl Viologen, Nanohybrids, Silicon Quantum Dots, Turn-On-Off-On sensing",

author = "Kalimuthu Rajendran and {Mohamed Nabeel}, Mattath and Kannaiyan Pandian and Velu Manikandan and Sivarasan Ganesan and Lo, {Huang Mu} and Nagappan Rajendiran and Xinghui Liu and {Samuel Oluwafemi}, Oluwatobi",

note = "Publisher Copyright: {\textcopyright} 2023 Elsevier B.V.",

year = "2024",

month = feb,

doi = "10.1016/j.microc.2023.109803",

language = "English",

volume = "197",

journal = "Microchemical Journal",

issn = "0026-265X",

publisher = "Elsevier Inc.",

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T1 - Fabrication of silicon quantum dots-methyl viologen nanohybrids

T2 - Turn-On-Off-On fluorescence nanoprobe for the detection of d-penicillamine

AU - Rajendran, Kalimuthu

AU - Mohamed Nabeel, Mattath

AU - Pandian, Kannaiyan

AU - Manikandan, Velu

AU - Ganesan, Sivarasan

AU - Lo, Huang Mu

AU - Rajendiran, Nagappan

AU - Liu, Xinghui

AU - Samuel Oluwafemi, Oluwatobi

PY - 2024/2

Y1 - 2024/2

N2 - This study provides a straightforward, one-step hydrothermal approach for synthesizing water-soluble silicon quantum dots (SiQDs). The surface of the synthesized SiQDs is modified by the carboxylic acid functional group (A:SiQDs) after succinic anhydride treatment. The modified A:SiQDs, which emitted blue light fluorescence, showed high stability against photobleaching, thermal stability, and good water solubility. The A:SiQDs are conjugated with methyl viologen (MV2+) to develop a nanohybrid for specific D-Penicillamine (D-PA) detection with an LOD of 8 nM. The suggested sensor was effectively used to analyze D-PA in commercial pharmaceutical formulations using the conventional addition method, and it produced results with good accuracy and precision that were nearly equal to those measured.

AB - This study provides a straightforward, one-step hydrothermal approach for synthesizing water-soluble silicon quantum dots (SiQDs). The surface of the synthesized SiQDs is modified by the carboxylic acid functional group (A:SiQDs) after succinic anhydride treatment. The modified A:SiQDs, which emitted blue light fluorescence, showed high stability against photobleaching, thermal stability, and good water solubility. The A:SiQDs are conjugated with methyl viologen (MV2+) to develop a nanohybrid for specific D-Penicillamine (D-PA) detection with an LOD of 8 nM. The suggested sensor was effectively used to analyze D-PA in commercial pharmaceutical formulations using the conventional addition method, and it produced results with good accuracy and precision that were nearly equal to those measured.

KW - D-Penicillamine

KW - Methyl Viologen

KW - Nanohybrids

KW - Silicon Quantum Dots

KW - Turn-On-Off-On sensing

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U2 - 10.1016/j.microc.2023.109803

DO - 10.1016/j.microc.2023.109803

M3 - Article

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SN - 0026-265X

VL - 197

JO - Microchemical Journal

JF - Microchemical Journal

M1 - 109803

ER -

Fabrication of silicon quantum dots-methyl viologen nanohybrids: Turn-On-Off-On fluorescence nanoprobe for the detection of d-penicillamine

Abstract

Keywords

ASJC Scopus subject areas

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New Quantum Dots Study Findings Have Been Reported by Investigators at University of Johannesburg (Fabrication of Silicon Quantum Dots-methyl Viologen Nanohybrids: Turn-on-off-on Fluorescence Nanoprobe for the Detection of D-penicillamine)

Cite this

Fabrication of silicon quantum dots-methyl viologen nanohybrids: Turn-On-Off-On fluorescence nanoprobe for the detection of d-penicillamine

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Press/Media

New Quantum Dots Study Findings Have Been Reported by Investigators at University of Johannesburg (Fabrication of Silicon Quantum Dots-methyl Viologen Nanohybrids: Turn-on-off-on Fluorescence Nanoprobe for the Detection of D-penicillamine)

Cite this